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Items: 8

1.
Full record GDS5809

Anti-leukemia drug etoposide effect on ecotropic viral integration site 1-overexpressing myeloid cells

Analysis of myeloid cell line U937 overexpressing ecotropic viral integration site 1 (EVI1) and cultured in the presence of antileukemic drug etoposide. Results provide insight into molecular mechanisms through which EVI1 confers resistance to drugs used in myeloid leukemia therapy.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 protocol sets
Platform:
GPL11532
Series:
GSE66660
8 Samples
Download data: CEL
2.
Full record GDS5432

Age effect on corneal endothelium

Analysis of corneal endothelium from pediatric (4-11 years old) and adult (53-70 years old) donor corneas. Results provide insight into differential molecular expression between pediatric and adult corneal endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 age sets
Platform:
GPL11532
Series:
GSE58315
9 Samples
Download data: CEL
3.
Full record GDS5388

Glucosamine treatment effect on KMH2 malignant lymphocytes

Analysis of Hodgkin lymphoma-derived cell line KMH2 treated with glucosamine (GlcN) for 24 hr. GlcN induces the posttranslational modification of proteins with O-linked β-N-acetylglucosamine (O-GlcNAc). Results provide insight into the molecular mechanisms activated following GlcN intake.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL11532
Series:
GSE49185
6 Samples
Download data: CEL
4.
Full record GDS5671

Notch1 stimulation effect on glioblastoma stem cell cultures

Analysis of Gb4 and Gb7 glioma cancer stem cells following forced expression of the Notch1 intracellular domain (NICD) to activate the Notch1 signaling pathway. Results provide insight into a role for the Notch1 pathway in glioblastoma stem cell plasticity and angiogenic properties.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 cell type, 2 genotype/variation sets
Platform:
GPL11532
Series:
GSE44561
8 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5671
ID:
5671
5.
Full record GDS4764

Dual specificity phosphatase-4 loss effect on basal-like breast cancer cell lines

Analysis of basal-like breast cancer (BLBC) cell lines following DUSP4-knockdown or MAP-ERK kinase (MEK)-inhibition with AZD6244/selumetinib (up to 24hr). Results provide insight into role of DUSP4 in promoting cancer stem cell-like phenotypes in BLBC.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 cell line, 2 genotype/variation, 3 protocol sets
Platform:
GPL11532
Series:
GSE41816
36 Samples
Download data: CEL
6.
Full record GDS4881

Postbariatric, morbidly obese patients with nonalcoholic fatty liver disease: liver biopsies

Analysis of liver from morbidly obese patient representing nonalcoholic fatty liver disease (NAFLD) subtypes steatosis and nonalcoholic steatohepatitis (NASH), post-bariatric surgery. Results provide insight into molecular basis of the NAFLD liver phenotypes and into postbariatric molecular changes.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 disease state, 3 protocol sets
Platform:
GPL11532
Series:
GSE48452
73 Samples
Download data: CEL
DataSet
Accession:
GDS4881
ID:
4881
7.
Full record GDS4598

Keratinocyte response to endogenous microRNA-31 inhibition

Analysis of keratinocytes transfected with microR-31 (miR-31) hairpin inhibitor for 48hrs. MiR-31 is one of the most highly overexpressed miRNAs in psoriasis skin. Results provide insight into the biological role of miR-31 in keratinocytes.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL11532
Series:
GSE41905
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4598
ID:
4598
8.
Full record GDS3981

Resveratrol (resVida) effect on obese men: vastus lateralis muscle biopsies

Analysis of vastus lateralis muscle from obese men after 30 days of resveratrol supplementation. Resveratrol, a calorie restriction mimetic, significantly reduced sleeping and resting metabolic rate. Results provide insight into molecular mechanisms underlying the metabolic effects of resveratrol.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL11532
Series:
GSE32357
20 Samples
Download data: CEL
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