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Items: 1 to 20 of 170

1.

The whole transcriptome expression profiling of human macrophages; comparison between control and human milk exosomes capsulated oligosaccharides treatment

(Submitter supplied) To discover the regulatory role of human milk exosomes oligosaccharides, The full cDNA was extracted from human macrophages and then compared the expression profiles of them to discovery the key features regulated by human milk exosomes extracted oligosaccharides.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
4 Samples
Download data: CEL
Series
Accession:
GSE163125
ID:
200163125
2.

Adipocytes induce melanoma plasticity by sensitizing cells to TGFb

(Submitter supplied) Transcriptome analysis of: 1- WM1716 melanoma cell line transfected with scrambled control or with miR-211. 2- WM3682 cell line mono-cultured or co-cultured with adipocytes.
Organism:
Homo sapiens; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL11532 GPL19117
6 Samples
Download data: CEL
Series
Accession:
GSE119478
ID:
200119478
3.

Disruption of Y chromosome expression in male lung cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
360 Samples
Download data: CEL
Series
Accession:
GSE151103
ID:
200151103
4.

Disruption of Y chromosome expression in male lung cancer: replication

(Submitter supplied) Lung cancer is the single most frequent cause of cancer death worldwide and is relatively more common in males. For reasons that are currently unknown, lung cancer is also associated with significantly worse outcomes in men than women. Here we replicate clustering of Y-chromosome transcripts identified previously as showing tumor-specific disruption in men with lung cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
123 Samples
Download data: CEL
Series
Accession:
GSE151102
ID:
200151102
5.

Disruption of Y chromosome expression in male lung cancer: discovery

(Submitter supplied) Lung cancer is the single most frequent cause of cancer death worldwide and is relatively more common in males. For reasons that are currently unknown, lung cancer is also associated with significantly worse outcomes in men than women. Here we examine the pulmonary transcriptome in lung cancer at a systems level through network analysis. We compare gene expression networks in affected and unaffected tissue derived from 126 patients with lung cancer. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
237 Samples
Download data: CEL
Series
Accession:
GSE151101
ID:
200151101
6.

Transcriptome-based identification of the beneficial role of blackcurrant, strawberry and yellow onion to attenuate the cytopathic effects of Clostridium difficile toxins

(Submitter supplied) Background: Human intestinal tissue samples are barely accessible to study potential health benefits of nutritional compounds. Numbers of animals used in animal trials, however, need to be minimalized. Therefore, in this study we explored the applicability of an in vitro model, namely human intestinal Caco-2 cells, to study the effect of food compounds on (intestinal) health. In vitro digested yellow (YOd) and white onion extracts (WOd) were used as model food compounds and transcriptomics was applied to obtain more insight into their mode of actions in the intestinal cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
15 Samples
Download data: CEL
Series
Accession:
GSE100541
ID:
200100541
7.

Expression data from normal human cerebellum

(Submitter supplied) Affimetrix Human Gene 1.1 ST Array profiling of 13 normal human cerebellum samples. Total RNA from 8 fetal brains and 5 adult brains was obtained from the Biochain company.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
13 Samples
Download data: CEL
Series
Accession:
GSE167447
ID:
200167447
8.

Association of RERG Expression to Female Survival Advantage in Malignant Pleural Mesothelioma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL15496 GPL11532
177 Samples
Download data: CEL, TXT
Series
Accession:
GSE163722
ID:
200163722
9.

Association of RERG Expression to Female Survival Advantage in Malignant Pleural Mesothelioma I

(Submitter supplied) Sex differences in incidence, prognosis, and treatment response have been described for many cancers. In malignant pleural mesothelioma (MPM), a lethal disease associated with asbestos exposure, men outnumber women 4 to 1, but women consistently live longer than men following surgery-based therapy. This study investigated whether tumor expression of genes associated with estrogen signaling could potentially explain observed survival differences. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
131 Samples
Download data: CEL
Series
Accession:
GSE163720
ID:
200163720
10.

Ayurvedic herbal preparation supplementation does not improve metabolic health in impaired glucose tolerance subjects; observations from a randomised placebo controlled trial

(Submitter supplied) The increased usage of alternative Ayurvedic treatments as potential health-beneficial therapies emphasizes the importance of studying its efficacy in sound placebo-controlled intervention trials. An example of such a traditional Ayurvedic herbal preparation is Mohana Choorna, a mixture composed of 20 different herbs and used to prevent and treat type 2-diabetes (T2D). We studied the efficacy of “Mohana Choorna” on T2D-related parameters in subjects with impaired glucose tol-erance. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
26 Samples
Download data: CEL
Series
Accession:
GSE164934
ID:
200164934
11.

A low meal frequency improves 24h metabolic and gene expression profiles in subjects with impaired glucose tolerance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
77 Samples
Download data: CEL
Series
Accession:
GSE52028
ID:
200052028
12.

A low meal frequency improves 24h metabolic and gene expression profiles in subjects with impaired glucose tolerance (muscle)

(Submitter supplied) Meal frequency regulates postprandial glucose and insulin responses, which may affect substrate partitioning and thus weight control. This study investigated the effects of meal frequency on the metabolic and transcriptomic profiles in subjects with impaired glucose tolerance (IGT). Eleven IGT (2h glucose; 9.0±0.3mmol/L) men stayed 2x 36 hours in a respiration chamber to measure substrate partitioning. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
16 Samples
Download data: CEL
Series
Accession:
GSE52027
ID:
200052027
13.

A low meal frequency improves 24h metabolic and gene expression profiles in subjects with impaired glucose tolerance (PBMC)

(Submitter supplied) Meal frequency regulates postprandial glucose and insulin responses, which may affect substrate partitioning and thus weight control. This study investigated the effects of meal frequency on the metabolic and transcriptomic profiles in subjects with impaired glucose tolerance (IGT). Eleven IGT (2h glucose; 9.0±0.3mmol/L) men stayed 2x 36 hours in a respiration chamber to measure substrate partitioning. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
61 Samples
Download data: CEL
Series
Accession:
GSE52026
ID:
200052026
14.

Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
50 Samples
Download data: CEL
Series
Accession:
GSE156249
ID:
200156249
15.

Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers. [A391]

(Submitter supplied) Background: Cold acclimation and exercise training were previously shown to increase peripheral insulin sensitivity in human volunteers with type 2 diabetes. Although cold is a potent activator of brown adipose tissue, the increase in peripheral insulin sensitivity by cold is largely mediated by events occurring in skeletal muscle and at least partly involves GLUT4 translocation, as is also observed for exercise training. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
14 Samples
Download data: CEL
Series
Accession:
GSE156248
ID:
200156248
16.

Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers. [A294]

(Submitter supplied) Background: Cold acclimation and exercise training were previously shown to increase peripheral insulin sensitivity in human volunteers with type 2 diabetes. Although cold is a potent activator of brown adipose tissue, the increase in peripheral insulin sensitivity by cold is largely mediated by events occurring in skeletal muscle and at least partly involves GLUT4 translocation, as is also observed for exercise training. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
36 Samples
Download data: CEL
Series
Accession:
GSE156247
ID:
200156247
17.

Expression data from Patient-derived tumor models (PDX) establish from bone metastases and match human breast primary tumor.

(Submitter supplied) A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Bone is the most common metastatic site in ER+ patients, however bone metastases are technically challenging to biopsy and analyse. Difficulties concern both tumour tissue acquisition and techniques for analysis and RNA extractions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
11 Samples
Download data: CEL
Series
Accession:
GSE146661
ID:
200146661
18.

BRCAness, SLFN11 and RB1 loss predict response to topoisomerase I inhibitors in triple negative breast cancers

(Submitter supplied) Expression data from patient-derived xenografts of human triple-negative breast cancers
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
30 Samples
Download data: CEL
Series
Accession:
GSE142639
ID:
200142639
19.

Expression data of HEL cells with or without LY2784544 and GRN163L

(Submitter supplied) The mutant JAK2v617F is a driver of myeloproliferative neoplasms(MPNs). Consequently, several JAK2 inhibitors are currently being studied in clinical trials. The most investigated JAK2 inhibitor, Ruxolitinib, provides significant and sustained improvements in spleen related and constitutional symptoms secondary to the disease and represents a milestone in the treatment of myelofibrosis. However, JAK2 inhibitors are non-curative and murine experiments have shown that JAK2 inhibitors don?t eradicate MPN stem cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
8 Samples
Download data: CEL
Series
Accession:
GSE141602
ID:
200141602
20.

TGFβ1 determines the fate of human adipose-derived stromal cells by restraining their immaturity and white/beige adipocyte potentials

(Submitter supplied) Human adipose-derived stem/stromal cells (hASCs) can differentiate into a large broad of specialized cell types to ensure homeostasis of tissues. Thus, they are drawing increasing attention in cell therapy and regenerative medicine. However, culture conditions are still critical to ensure their regenerative capabilities. Here we compared Standard conditions (αMEM containing 10% fetal bovine serum) and Endothelial cell Growth Medium 2 (EGM2) containing few serum (2% v/v) for expansion of hASCs. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
11 Samples
Download data: CEL
Series
Accession:
GSE136778
ID:
200136778
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