GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Methylation profiling by genome tiling array

Platforms:

GPL23572 GPL16304 GPL21145

46 Samples

Download data: IDAT, TXT

(Submitter supplied) DNA methylation changes specific for healthy undifferentiated and differentiated human gastric primary epithelial cells of different regions of the stomach were here determined in order to describe the epigenetic profile of these cells in correlation to their gene expression pattern.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL21145 GPL16304

24 Samples

Download data: IDAT

(Submitter supplied) This work reveals the effect of antipsychotics on DNA methylation using the cell model. After the treatment of antipsychotics, haloperidol and risperidone, DNA methylation profiles obtained by Illumina HumanMethylation450 beadchip were examined.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

18 Samples

Download data: TXT

(Submitter supplied) Genome wide Methylation profiling of DNA extracted from plaques of atherosclerotic plaque samples (n=14) and of controls (n=4). The Illumina Infinium HumanMethylation450 or HumanMethylation850 BeadChip was used representing potentially methylated CpG sites throughout the genome.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL23976 GPL16304

18 Samples

Download data: IDAT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL16304 GPL21145

1137 Samples

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(Submitter supplied) Smoking is common in people who live with HIV infection and has significant adverse effects on HIV outcomes. The impacts of smoking on methylome has been well established in non-HIV populations. However, the smoking’s effects on host methylome in HIV-positive population has not been investigated and it is unknown if smoking-associated DNA methylation link to HIV outcomes. In this study, we applied machine learning methods selected smoking-associated DNA methylation features to predict HIV related frailty and mortality.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

608 Samples

Download data: TXT

(Submitter supplied) DNA methylation profiling of NeuN+sorted neuronal nuclei from post-mortem brain tissue of Multiple Sclerosis (MS) patients (n=10) (MS) and non-neurological controls (n=7) (non-MS). Genomic DNA was subjected to conventional BS-treatment as well as oxidative BS (oxBS)-conversion using TrueMethylTM 96 kit of CEGXTM (Cambridge Epigenetix Limited) to allow for subsequent detection of hydroxymethylation (5hmC = BS - oxBS).

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

34 Samples

Download data: IDAT

(Submitter supplied) We measured 371 genome‐wide DNA methylation profiles of sorted peripheral blood samples from 63 patients with rheumatoid arthritis and 31 unaffected control subjects. Methylation profiles were measured for cell subsets of CD14+ monocytes, CD19+ B cells, CD4+ memory T cells, and CD4+ naive T cells.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

371 Samples

Download data: IDAT, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

138 Samples

Download data: IDAT

(Submitter supplied) Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 28 healthy controls and7 FASD patients.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

35 Samples

Download data: IDAT, TXT

(Submitter supplied) Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 64 healthy controls and 39 FASD patients.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

103 Samples

Download data: IDAT, TXT

(Submitter supplied) Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM), which is associated with a very poor prognosis. Specific molecular patterns distinguish pPCL in comparison to MM and in relation to main genomic alterations. In the present study, a whole-genome methylation profiling analysis by high-density array revealed a global gene hypomethylation profile in pPCL. Lower methylation levels were particularly observed in the promoter and 5’ untranslated regions (5’UTR), whereas higher levels were evidenced in gene body or 3’ untranslated regions (3’UTR). more...

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

14 Samples

Download data: IDAT, TXT

(Submitter supplied) Combined EPIC and 450k analysis across 212 posterior fossa ependymoma's classified as PFB using the Heidelberg Brain Tumour Classifier Methylation profiling across 212 posterior fossa PFB ependymoma's to discern molecular heterogeneity

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL16304 GPL21145

212 Samples

Download data: IDAT, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Methylation profiling by array; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms

19 Samples

Download data: IDAT, NARROWPEAK, TXT

(Submitter supplied) While Illumina X technology has helped to reduce the cost of whole genome sequencing substantially, its application for bisulphite sequencing is not straightforward. We describe the optimization of a library preparation and sequencing approach that maximizes the yield and quality of sequencing, and how to eliminate a previously unrecognized artefact affecting several percent of bisulphite sequencing reads.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL16304

8 Samples

Download data: IDAT, TXT

(Submitter supplied) Genome wide DNA methylation from peripheral white blood cells (PWBCs) from individuals from different cohorts included in the MENA project. Samples included 474 individuals (DiOGenes-UNAV n=52, OBEPALIP n=29, Food4Me-UNAV n=39, GEDYMET n=57, ICTUS n=7, NUGENOB-UNAV n=22, PREDIMED-UNAV n=116, RESMENA n=44, OBEKIT n=96, and NormoP n=12). The Illumina Infinium 450k Human DNA methylation Beadchip or Infinium MethylationEPIC Beadchip (for OBEKIT) was used to obtain DNA methylation profiles across approximately 450,000 CpGs in these samples.

Organism:

Homo sapiens

Type:

Methylation profiling by array; Methylation profiling by genome tiling array

Platforms:

GPL21145 GPL16304

474 Samples

Download data: IDAT, TXT

(Submitter supplied) Epigenetic (N=15) were based on the Illumina Infinium HumanMethylation450 BeadChip. We searched for differentially methylated probes (DMPs) and regions (DMRs).

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

15 Samples

Download data: IDAT, TXT

(Submitter supplied) The aim of this study was to identify DNA methylation patterns in femur trabecular bone and cartilage of age-matched female baboons, five with and five without knee osteoarthritis. The Illumina Infinium Human Methylation450 BeadChip was used to assess these genome-wide methylation patterns.

Organism:

Papio sp.; Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

20 Samples

Download data: CSV, IDAT

(Submitter supplied) Epigenetic and genetic profiles (N=67) were based on the Illumina Infinium HumanMethylation450 BeadChip. We searched for differentially methylated probes (DMPs) and regions (DMRs). For genetic associations we analyzed the CpG-SNPs present on the array

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL16304

67 Samples

Download data: IDAT, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL16304 GPL21145

791 Samples

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