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Items: 1 to 20 of 205

1.

Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus; Mus musculus; Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL18609 GPL18615
340 Samples
Download data: CEL, GPR, TXT
Series
Accession:
GSE72088
ID:
200072088
2.

Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity (mRNA)

(Submitter supplied) The well-defined battery of in vitro systems applied within chemical cancer risk assessment is often characterised by a high false-positive rate, thus repeatedly failing to correctly predict the in vivo genotoxic and carcinogenic properties of test compounds. Toxicogenomics, i.e. mRNA-profiling, has been proven successful in improving the prediction of genotoxicity in vivo and the understanding of underlying mechanisms. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL18615
184 Samples
Download data: CEL
Series
Accession:
GSE72081
ID:
200072081
3.

Stretch-dependent genes in vascular smooth muscle cells

(Submitter supplied) Vascular smooth muscle cells (VSMCs) respond to biomechanical stretch with specific changes in gene expression which govern the phenotype of these cells. The mechanotransducer zyxin is a potential candidate for regulating the expression of such genes. Using microarrays, we compared stretch-induced gene expression in wild type and zyxin-null VSMCs to define such changes in detail.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL18615
11 Samples
Download data: CEL
Series
Accession:
GSE60447
ID:
200060447
4.

Evaluating mRNA and microRNA profiles reveals discriminative and compound-specific responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus; Mus musculus; Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL18609 GPL18615
120 Samples
Download data: CEL, GPR, TXT
Series
Accession:
GSE57132
ID:
200057132
5.

Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes [Affymetrix]

(Submitter supplied) The study investigated differential gene expression in primary mouse hepatocyte mRNA following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological replicates per compound/solvent.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL18615
60 Samples
Download data: CEL
Series
Accession:
GSE57129
ID:
200057129
6.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
7.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array [CDF: Mouse4302_Mm_ENTREZG.cdf Brainarray version 17.0.0]

(Submitter supplied) http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/17.0.0/entrezg.asp Protocol: This is identical to GPL1261 but a custom cdf environment was used to extract data. The cdf can be found at the link below.
Organism:
Mus musculus
5 Series
1 Related Platform
198 Samples
Download data: CDF, TXT
Platform
Accession:
GPL18615
ID:
100018615
8.

TBTO_48h_Exp3

Organism:
Mus musculus
Source name:
TBTO_48h_Exp3
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854413
ID:
301854413
9.

TBTO_48h_Exp2

Organism:
Mus musculus
Source name:
TBTO_48h_Exp2
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854412
ID:
301854412
10.

TBTO_48h_Exp1

Organism:
Mus musculus
Source name:
TBTO_48h_Exp1
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854411
ID:
301854411
11.

TBTO_24h_Exp3

Organism:
Mus musculus
Source name:
TBTO_24h_Exp3
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854410
ID:
301854410
12.

TBTO_24h_Exp2

Organism:
Mus musculus
Source name:
TBTO_24h_Exp2
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854409
ID:
301854409
13.

TBTO_24h_Exp1

Organism:
Mus musculus
Source name:
TBTO_24h_Exp1
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854408
ID:
301854408
14.

Resorcinol_48h_Exp3

Organism:
Mus musculus
Source name:
Resorcinol_48h_Exp3
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854407
ID:
301854407
15.

Resorcinol_48h_Exp2

Organism:
Mus musculus
Source name:
Resorcinol_48h_Exp2
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854406
ID:
301854406
16.

Resorcinol_48h_Exp1

Organism:
Mus musculus
Source name:
Resorcinol_48h_Exp1
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854405
ID:
301854405
17.

Resorcinol_24h_Exp3

Organism:
Mus musculus
Source name:
Resorcinol_24h_Exp3
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854404
ID:
301854404
18.

Resorcinol_24h_Exp2

Organism:
Mus musculus
Source name:
Resorcinol_24h_Exp2
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854403
ID:
301854403
19.

Resorcinol_24h_Exp1

Organism:
Mus musculus
Source name:
Resorcinol_24h_Exp1
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854402
ID:
301854402
20.

Res_48h_Exp3

Organism:
Mus musculus
Source name:
Res_48h_Exp3
Platform:
GPL18615
Series:
GSE72081 GSE72088
Download data: CEL
Sample
Accession:
GSM1854401
ID:
301854401
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