GPL18615[RGSE] - GEO DataSets

Select item 2000720881.

Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus; Homo sapiens; Mus musculus

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL18615 GPL18609
340 Samples

Download data: CEL, GPR, TXT

Series

Accession:: GSE72088

ID:: 200072088

Select item 2000720812.

Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity (mRNA)

(Submitter supplied) The well-defined battery of in vitro systems applied within chemical cancer risk assessment is often characterised by a high false-positive rate, thus repeatedly failing to correctly predict the in vivo genotoxic and carcinogenic properties of test compounds. Toxicogenomics, i.e. mRNA-profiling, has been proven successful in improving the prediction of genotoxicity in vivo and the understanding of underlying mechanisms. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL18615
184 Samples

Download data: CEL

Series

Accession:: GSE72081

ID:: 200072081

Select item 2000604473.

Stretch-dependent genes in vascular smooth muscle cells

(Submitter supplied) Vascular smooth muscle cells (VSMCs) respond to biomechanical stretch with specific changes in gene expression which govern the phenotype of these cells. The mechanotransducer zyxin is a potential candidate for regulating the expression of such genes. Using microarrays, we compared stretch-induced gene expression in wild type and zyxin-null VSMCs to define such changes in detail.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL18615
11 Samples

Download data: CEL

Series

Accession:: GSE60447

ID:: 200060447

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000571324.

Evaluating mRNA and microRNA profiles reveals discriminative and compound-specific responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus; Homo sapiens; Mus musculus

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL18609 GPL18615
120 Samples

Download data: CEL, GPR, TXT

Series

Accession:: GSE57132

ID:: 200057132

Select item 2000571295.

Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes [Affymetrix]

(Submitter supplied) The study investigated differential gene expression in primary mouse hepatocyte mRNA following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological replicates per compound/solvent.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL18615
60 Samples

Download data: CEL

Series

Accession:: GSE57129

ID:: 200057129

GEO DataSets

Functional Genomics Studies

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