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Items: 1 to 20 of 108

1.

Oral Regeneration Is the Default Pathway Triggered by Injury in Hydra

(Submitter supplied) Animals capable of whole-body regeneration can fully restore any tissue lost due to injury. Because different types of injury may require the regeneration of different structures, transcription during whole-body regeneration needs to dynamically adapt to meet the requirements specific to any given injury. However, the regulatory mechanisms responsible for modulating the transcriptional response to injury are poorly understood at the molecular level. more...
Organism:
Hydra vulgaris
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL28733 GPL25712
113 Samples
Download data: BED, BW, CSV, MATRIX, RDATA
Series
Accession:
GSE152994
ID:
200152994
2.

PIWI-piRNA pathway mediated transposon repression in Hydra somatic stem cells

(Submitter supplied) Transposable elements (TEs) can damage genomes, thus organisms employ a variety of mechanisms to repress TE expression. The PIWI-piRNA pathway is a small RNA pathway that represses TE expression in the germline of animals. Here we explore the function of the pathway in the somatic stem cells of Hydra, a long-lived freshwater cnidarian. Hydra have three stem cell populations, all of which express PIWI proteins; endodermal and ectodermal epithelial stem cells are somatic, whereas the interstitial stem cells have germline competence. more...
Organism:
Hydra vulgaris
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL25712 GPL27013
12 Samples
Download data: TXT
Series
Accession:
GSE135440
ID:
200135440
3.

Stem cell differentiation trajectories in Hydra resolved at single cell resolution

(Submitter supplied) The adult Hydra polyp continuously renews all of its cells using three separate stem cell populations but the genetic pathways enabling these dynamic tissue properties are not well understood. We used Drop-seq to sequence 24,985 Hydra cells and identified the molecular signatures of a broad spectrum of cell states, from stem cells to terminally differentiated cells. We constructed differentiation trajectories for each cell lineage and identified the transcription factors expressed along these trajectories, thus creating a comprehensive map of all developmental lineages in the adult animal. more...
Organism:
Hydra vulgaris
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL25713 GPL25712
24 Samples
Download data: BED, TXT
Series
Accession:
GSE121617
ID:
200121617
4.

Illumina HiSeq 4000 (Hydra vulgaris)

Organism:
Hydra vulgaris
3 Series
104 Samples
Download data
Platform
Accession:
GPL25712
ID:
100025712
5.

8F3_RNA: Foot regeneration RNA-seq, 8 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632765
ID:
304632765
6.

8F2_RNA: Foot regeneration RNA-seq, 8 hours post amputation, replicate 2

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632764
ID:
304632764
7.

8F1_RNA: Foot regeneration RNA-seq, 8 hours post amputation, replicate 1

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632763
ID:
304632763
8.

8H3_RNA: Head regeneration RNA-seq, 8 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632762
ID:
304632762
9.

8H2_RNA: Head regeneration RNA-seq, 8 hours post amputation, replicate 2

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632761
ID:
304632761
10.

8H1_RNA: Head regeneration RNA-seq, 8 hours post amputation, replicate 1

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632760
ID:
304632760
11.

3F3_RNA: Foot regeneration RNA-seq, 3 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632759
ID:
304632759
12.

3F2_RNA: Foot regeneration RNA-seq, 3 hours post amputation, replicate 2

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632758
ID:
304632758
13.

3F1_RNA: Foot regeneration RNA-seq, 3 hours post amputation, replicate 1

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632757
ID:
304632757
14.

3H3_RNA: Head regeneration RNA-seq, 3 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632756
ID:
304632756
15.

3H2_RNA: Head regeneration RNA-seq, 3 hours post amputation, replicate 2

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632755
ID:
304632755
16.

3H1_RNA: Head regeneration RNA-seq, 3 hours post amputation, replicate 1

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632754
ID:
304632754
17.

0F3_RNA: Foot regeneration RNA-seq, 0 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632753
ID:
304632753
18.

0F2_RNA: Foot regeneration RNA-seq, 0 hours post amputation, replicate 2

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632752
ID:
304632752
19.

0F1_RNA: Foot regeneration RNA-seq, 0 hours post amputation, replicate 1

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632751
ID:
304632751
20.

0H3_RNA: Head regeneration RNA-seq, 0 hours post amputation, replicate 3

Organism:
Hydra vulgaris
Source name:
Mid-Body Column Tissue
Platform:
GPL25712
Series:
GSE152994
Download data
Sample
Accession:
GSM4632750
ID:
304632750
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