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Items: 2

1.

End resection and telomere healing of DNA double-strand breaks during nematode programmed DNA elimination

(Submitter supplied) Most DNA double-strand breaks (DSBs) are harmful to genome integrity. However, some forms of DSBs are essential to biological processes, such as meiotic recombination and V(D)J recombination. DSBs are also required for programmed DNA elimination (PDE) in ciliates and nematodes. In nematodes, the DSBs are healed with telomere addition. While telomere addition sites have been well-characterized, little is known regarding the DSBs that fragment nematode chromosomes. more...
Organism:
Parascaris univalens; Ascaris suum
Type:
Other
Platforms:
GPL31096 GPL31097 GPL34158
42 Samples
Download data: BW
Series
Accession:
GSE260958
ID:
200260958
2.

Small RNA pathways in the nematode Ascaris in the absence of piRNAs

(Submitter supplied) Small RNA pathways play diverse regulatory roles in the nematode C. elegans. However, our understanding of small RNA pathways, their conservation, and their roles in other nematodes is limited. Here, we analyzed small RNA pathways in the parasitic nematode Ascaris. Ascaris has ten Argonautes with five worm-specific Argonautes (WAGOs) that are associated with secondary 5’-triphosphate small RNAs (22-24G-RNAs). more...
Organism:
Ascaris suum
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL31096 GPL31097
143 Samples
Download data: FA
Series
Accession:
GSE189061
ID:
200189061

Supplemental Content

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