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Items: 5

1.

TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer

(Submitter supplied) Background: Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical care. The aim of this study was to evaluate the prognostic value of gene expression-based classification along with established prognostic markers and mutation status of the TP53 gene, in a group of breast cancer patients with long-term (12-16 years) follow-up. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
5 related Platforms
81 Samples
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Series
Accession:
GSE40954
ID:
200040954
2.

Smooth Muscle Cells

(Submitter supplied) This set contains 68 arrays of two series of experiments. 60 arrays are used to profile the heterogeneity of SMCs from different anatomic locations. 8 arrays are used to profile the change of gene expression of vascular smooth muscle cells upon serum exposure. An all pairs experiment design type is where all labeled extracts are compared to every other labeled extract. Keywords: all_pairs
Organism:
Homo sapiens
Type:
Expression profiling by array
4 related Platforms
68 Samples
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Series
Accession:
GSE7195
ID:
200007195
3.

Genome-wide characterization of gene expression variations and DNA copy number changes in prostate cancer cell lines

(Submitter supplied) Abstract: BACKGROUND: The aim of this study was to characterize gene expression and DNA copy number profiles in androgen sensitive (AS) and androgen insensitive (AI) prostate cancer cell lines on a genome-wide scale. METHODS: Gene expression profiles and DNA copy number changes were examined using DNA microarrays in eight commonly used prostate cancer cell lines. Chromosomal regions with DNA copy number changes were identified using cluster along chromosome (CLAC). more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by array
Platforms:
GPL3355 GPL3341
16 Samples
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Series
Accession:
GSE4396
ID:
200004396
4.

Gene expression variations in prostate cancer cell lines

(Submitter supplied) Abstract: BACKGROUND: The aim of this study was to characterize gene expression and DNA copy number profiles in androgen sensitive (AS) and androgen insensitive (AI) prostate cancer cell lines on a genome-wide scale. METHODS: Gene expression profiles and DNA copy number changes were examined using DNA microarrays in eight commonly used prostate cancer cell lines. Chromosomal regions with DNA copy number changes were identified using cluster along chromosome (CLAC). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1699
Platform:
GPL3341
8 Samples
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Series
Accession:
GSE4016
ID:
200004016
5.

Molecular targets of doxazosin in human prostatic stromal cells

(Submitter supplied) BACKGROUND: We used cDNA microarray analysis to obtain insights into the mechanisms of action of doxazosin, an alpha(1)-adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH). METHODS: Hierarchical clustering analysis and significance analysis of microarray (SAM) were performed to identify genes differentially expressed between untreated stromal cells cultured from normal tissue and BPH, and changes in gene expression induced by doxazosin. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL3341 GPL3340 GPL3323
18 Samples
Download data
Series
Accession:
GSE4010
ID:
200004010
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