Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 421

1.

Effect of tumor necrosis factor receptor (Tnfr) deletion in ozone-induced pulmonary transcriptome changes in mice

(Submitter supplied) Background: Ozone (O3) is the predominant oxidant air pollutant associated with respiratory inflammation, lung dysfunction, and worsening preexisting airway diseases. We determined that TNFR signlaing pathway plays a key role in lung injury and inflammation caused by O3 in mice. However, downstream molecular mechanisms underlying TNFR pathway have not been investigated. Methods: To investigate the role of TNFR pathway in gene expression changes, Tnfr1/2-deficient (Tnfr-/-) and wild-type (Tnfr+/+, C57BL/6J) mice were exposed to air or 0.3-ppm O3. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
24 Samples
Download data: CEL, CHP
Series
Accession:
GSE166399
ID:
200166399
2.

Expression data (mRNA) from GD-9.5 (E9.5), Folr1+/+ (Folr1 WT) and Folr-/- (Folr1 KO) mouse embryos

(Submitter supplied) Folic acid is a nutrient essential for embryonic development. Folate deficiency can cause embryolethality or neural tube defects and orofacial anomalies. Folate receptor 1 (Folr1), is a folate binding protein that facilitates the cellular uptake of dietary folate. Animal studies highlighted critical roles of folate in embryogenesis including orofacial development. Orofacial clefts were observed in the offspring of experimental animals on folic acid-deficient diets. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
5 Samples
Download data: CEL, CHP
Series
Accession:
GSE155428
ID:
200155428
3.

Sexually dimorphic characteristics of the small intestinal transcriptome of Fabp-gene ablated mice

(Submitter supplied) Analysis of whole small intestine tissue of 10-week old C57BL/6J mice, C57BL/6J mice with the disruption of either Fabp2 gene or Fabp6 gene, and C57BL/6J mice with the simultaneous disruption of Fabp2 and Fabp6 genes. Fabp2 and Fabp6 are two types of fatty acid binding proteins expressed primarily in the small intestine.
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL339 GPL340
32 Samples
Download data: CEL, CSV
Series
Accession:
GSE128862
ID:
200128862
4.

Expression data from livers of 6 and 10-weeks garlic-fed mice

(Submitter supplied) Garlic is a popular flavor enhancer in modern cuisines. Although anti-atherosclerotic, anti-proliferative, hypolipidemic and chemopreventative effects of garlic are known for a long time, the mechanisms of garlic as a dietary supplement ramain largely unknown. We used microarrays to analyze the global programme of gene expression in control (cellulose) and garlic-fed C57BL/6J mice serendipitously infected with Pasteurella multocida and identified acute phase response genes, particularly Lcn2 and Orm2, as the major players in the innate response. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
12 Samples
Download data: CEL
Series
Accession:
GSE20093
ID:
200020093
5.

Analysis of the Effect of Fibulin-1 on Fibroblast Growth Factor 8 Signaling

(Submitter supplied) We have previously shown that human fibulin-1 (FBLN1) is a binding partner of fibroblast growth factor 8 (FGF8) and affects its expression and signaling. Herein, we investigate the mechanisms by which FBLN1 affects FGF8 signaling. Fibulin-1 (Fbln1) -deficiency in mouse embryo fibroblasts (MEF) caused downregulation of Fgf8 as well as fibroblast growth factor receptors (Fgfr) 1 and 3 and several downstream genes in the Fgf8 pathway, including Six1, Eya1 and Barx1. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
10 Samples
Download data: CEL
Series
Accession:
GSE102844
ID:
200102844
6.

Short-term Akt activation in cardiac muscle cells improves contractile dysfunction in failing hearts.

(Submitter supplied) Akt is a serine/threonine protein kinase that is activated by a variety of growth factors or cytokines in a PI3-kinase dependent manner. Using a conditional transgenic system in which Akt signaling can be turned on or off in the adult heart, we have recently demonstrated that short-term Akt activation induces a ‘physiological’ form of cardiac hypertrophy with enhanced coronary angiogenesis and maintained contractility. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL339 GPL340
18 Samples
Download data
Series
Accession:
GSE4728
ID:
200004728
7.

Expression data from from NOS2-deficient (NOS2-/-) and wild-type mice subjected to endotoxin or saline challenge

(Submitter supplied) Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated regions. Sepsis and endotoxemia impair HPV. We previously showed that nitric oxide synthase 2 (NOS2) is required, but not sufficient, for the effect of endotoxin on HPV. The aim of the current study was to identify additional factors that might contribute to the impairment of HPV during endotoxemia. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
17 Samples
Download data: CEL
Series
Accession:
GSE130936
ID:
200130936
8.

Role of skeletal muscle in lung development.

(Submitter supplied) Skeletal (striated) muscle is one of the four basic tissue types, together with the epithelium, connective and nervous tissues. Lungs, on the other hand, develop from the foregut and among various cell types contain smooth, but not skeletal muscle. Therefore, during earlier stages of development, it is unlikely that skeletal muscle and lung depend on each other. However, during the later stages of development, respiratory muscle, primarily the diaphragm and the intercostal muscles, execute so called fetal breathing-like movements (FBMs), that are essential for lung growth and cell differentiation. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL339 GPL340
4 Samples
Download data: CEL, CHP
Series
Accession:
GSE109783
ID:
200109783
9.

FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation

(Submitter supplied) To understand the developing striatum, key genes during development were identified using microarray analsyis tha could be considered as marker of medium spiny neurons. The ages studied is at peak striatal neurogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
9 Samples
Download data: CEL
Series
Accession:
GSE55497
ID:
200055497
10.

Expression data from small intestinal eosinophils and dendritic cells

(Submitter supplied) Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. We performed a global gene expression analysis to examine which genes are highly expressed by small intestinal eosinophils (CD11b+CD11c(int)MHCII-SiglecF+) compared with dendritic cells (CD11c+MHCII+).
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
2 Samples
Download data: CEL, CHP
Series
Accession:
GSE77545
ID:
200077545
11.

SCL and LMO1 reprogram thymocytes into self-renewing cells.

(Submitter supplied) The SCL and LMO1 oncogenic transcription factors reprogram thymocytes into self-renewing pre-leukemic stem cells (pre-LSCs). Here we report that SCL directly interacts with LMO1 to activate the transcription of a self-renewal program coordinated by LYL1.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
6 Samples
Download data: CEL
Series
Accession:
GSE74659
ID:
200074659
12.

On the relevance of technical variation due to building pools in microarray experiments

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Apis mellifera
Type:
Expression profiling by array
Platforms:
GPL339 GPL20903
66 Samples
Download data: CEL, GPR
Series
Accession:
GSE72944
ID:
200072944
13.

On the relevance of technical variation due to building pools in microarray experiments [Mouse]

(Submitter supplied) The objective of the study was to assess the technical error due to blending of individual samples into pools in experimental data. The blending error variance component corresponds to random effects for inaccuracies, which were modeled on the logarithmic scale of normalized gene expression. It's estimation based on a linear mixed model, fitted for each transcript.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
44 Samples
Download data: CEL
Series
Accession:
GSE72861
ID:
200072861
14.

Inactivation of Unr results in induction of differentiation of murine ES cells into the primitive endoderm lineage

(Submitter supplied) Unr (upstream of N-ras) is a cytoplasmic RNA-binding protein with cold shock domains, involved in regulation of messenger RNA stability and translation. To address the biological role of Unr, we inactivated the unr gene by homologous recombination in mice and embryonic stem (ES) cells. Embryos deficient for Unr die at mid-gestation, and the main phenotypic defects observed, growth deficiency and absence of neural tube closure, suggest a role of Unr in the balance proliferation/differentiation during early development. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
16 Samples
Download data: CEL, CHP, EXP
Series
Accession:
GSE17566
ID:
200017566
15.

Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

(Submitter supplied) We used microarrays to investigate gene expression changes in the pancreas of RasGrf1 KO mice. These animals have a reduction in the number and size of the pancreatic islets which lead to lower levels of insulin and glucagon in their blood.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
6 Samples
Download data: CEL
Series
Accession:
GSE56371
ID:
200056371
16.

Gene co-expression network analysis of myostatin regulation at three different mouse developmental timepoints

(Submitter supplied) Myostatin (Mstn) knockout mice exhibit large increases in skeletal muscle mass. However, relatively few of the genes that mediate or modify MSTN effects are known. In this study, we performed co-expression network analysis using whole transcriptome microarray data from Mstn-null and wild-type mice to identify genes involved in important biological processes and pathways related to skeletal muscle and adipose development.Genes differentially expressed between wild-type and Mstn-null mice were identified at 13.5 d.p.c. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL340 GPL339
60 Samples
Download data: CEL
Series
Accession:
GSE63154
ID:
200063154
17.

Gene expression profiles at the day 5 blastocyst implantation and interimplantation sites of the hamster

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus; Mesocricetus auratus
Type:
Expression profiling by array
Platforms:
GPL96 GPL339
12 Samples
Download data: CEL
Series
Accession:
GSE59474
ID:
200059474
18.

Gene expression profiles at the day 5 blastocyst implantation and interimplantation sites of the hamster [mouse array]

(Submitter supplied) Current knowledge of the molecular regulation of the blastocyst implantation event has been largely derived from studies in the mouse that requires ovarian estrogen for initiation of the implantation event. However, there are species such as the hamster, guinea pig, pig, horse, rhesus monkey and perhaps the human where the blastocyst implantation event initiates only in the progesterone-primed uterus. more...
Organism:
Mesocricetus auratus; Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
6 Samples
Download data: CEL
Series
Accession:
GSE59413
ID:
200059413
19.

Expression data from murine myogenic cells

(Submitter supplied) Skeletal muscle has great regenerative capacity, which is dependent on muscle stem cells, also known as satellite cells. We established the purification system of myogenic cells. We used microarrays to identify specific genes during the muscle regenerative process.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
4 Samples
Download data
Series
Accession:
GSE56903
ID:
200056903
20.

Polymicrobial periodontal pathogens transcriptomes in calvarial bone and soft tissue

(Submitter supplied) The objectives of this investigation were to examine changes in the host transcriptional profiles during a polymicrobial periodontal pathogens Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia infection using a murine calvarial model of inflammation and bone resorption. P. gingivalis FDC 381, T. denticola ATCC 35404, and T. forsythia ATCC 43037 was injected into the subcutaneous soft tissue over the calvaria of BALB/c mice for 3 days, after which the soft tissues and calvarial bones were excised. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
19 Samples
Download data: CEL
Series
Accession:
GSE29670
ID:
200029670
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GPL339[RGSE]|query=1|qty=8|blobid=MCID_616b27b145cdce07892ac262|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center