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Items: 1 to 20 of 83

1.

Type I Interferon Dependent Anti-viral Activity

(Submitter supplied) Synthetic oligonucleotides (ODN) expressing CpG motifs trigger an innate immune response via TLR9. Multiple microarray analyses were performed to identify the global effects on gene expression of stimulating the CAL-1 human pDC line with different types of CpG ODN. Results show that a subset of genes characterized by shared anti-viral activity was consistently up-regulated by ODNs that otherwise mediate discrete functions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3779
45 Samples
Download data: GPR
Series
Accession:
GSE30849
ID:
200030849
2.

Global effect of JTV or JTV-Alt overexpression in HeLa cells

(Submitter supplied) JTV is not only a structural component of multi-aminoacyl-tRNA synthetase complex, but also a regulator of FBP that in turn controls c-Myc expression. In order to identify JTV target genes other than FBP and c-Myc, JTV or JTV-Alt (alternatively spliced form of JTV, enriched in the nucleus) protein was over-expressed in HeLa cells and global gene expression changes were monitored using cDNA expression microarray.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3779
4 Samples
Download data: GPR
Series
Accession:
GSE13646
ID:
200013646
3.

Microarray profiling of expression patterns of fibroblasts from different skin types

(Submitter supplied) Adult human fibroblasts derived from the dermis of 4 mm punch biopsies taken from the lower backs of 15 healthy subjects of 3 different phototypes (types I, III and VI). This study was approved by the Human Research Ethics Committee of Hamburg. Subjects with type I skin were #4, 12, 15, 19 and 26; subjects with type III skin were # 6, 9, 13, 14 and 23, and subjects with type VI skin were # 7, 8, 16, 17 and 28. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3779
15 Samples
Download data: GPR
Series
Accession:
GSE22022
ID:
200022022
4.

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells

(Submitter supplied) The mechanism whereby IL-9 stimulated monocytes, promote proliferation of co-cultured ATL cells remains undefined. To obtain preliminary clues concerning this contribution, transcription profiles were obtained between monocytes derived from ATL patients and those derived from healthy donors as assessed by cDNA microarray. Keywords: disease state design
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3779
6 Samples
Download data: GPR
Series
Accession:
GSE10789
ID:
200010789
5.

RNAi analysis of the FBP transactivator family

(Submitter supplied) The FBP (FUSE Binding Protein) transcription factor family is composed of three highly related members; FBP/FBP1, FBP2, and FBP3. While they all share distinct modular protein structures and nucleic acid-binding specificities, their transactivator strength is graded and they also differ in their interaction with their protein partners. Especially from the extensive nuclear co-localization of these molecules, we anticipated that they co-regulate a set of common target genes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2573
Platform:
GPL3779
6 Samples
Download data: GPR
Series
Accession:
GSE4914
ID:
200004914
6.
Full record GDS2573

Far-upstream element binding protein inactivation

Analysis of primary skin fibroblasts (Hs68) following siRNA knockdown of far-upstream element binding protein (FBP) 1, 2, or 3. Results provide insight into the function of each member of the FBP transactivator family.
Organism:
Homo sapiens
Type:
Expression profiling by array, log2 ratio, 3 protocol sets
Platform:
GPL3779
Series:
GSE4914
6 Samples
Download data: GPR
7.

NCI/ATC Hs-OperonV3

(Submitter supplied) Microarrays are printed with GeneMachines robotic arrayer from Genomic Solutions (http://www.genomicsolutions.com) that is fitted with a printhead containing 48 SMP2.5 printing pins from Telechem International (http://www.arrayit.com). The human long oligonuleotide probe set contains 34,960 optimized 70mers (plus controls) obtained from Operon (http://www.operon.com/). The long oligonucleotide probes were purchased in 384-well polypropylene plates (Genetix, 384 microarray) and dissolved print buffer of sodium phosphate (150mM) at ph 8.5 and 4% sodium sulphate at a concentration of 20-30 uM. more...
Organism:
Homo sapiens
1 DataSet
5 Series
76 Samples
Download data
Platform
Accession:
GPL3779
ID:
100003779
8.

'D' ODN for 48 hours - repeat 3 - mAdbID:115405

Organism:
Homo sapiens
Source name:
Universal Human Reference RNA (channel 1) 'D' ODN for 48 hours (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765479
ID:
300765479
9.

'K' ODN + anti-INFR for 9 hours - repeat 1 - mAdbID:111779

Organism:
Homo sapiens
Source name:
'K' ODN + anti-INFR for 9 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765478
ID:
300765478
10.

'K' ODN for 9 hours - repeat 5 - mAdbID:111777

Organism:
Homo sapiens
Source name:
'K' ODN for 9 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765477
ID:
300765477
11.

'D' ODN for 27 hours - repeat 4 - mAdbID:109463

Organism:
Homo sapiens
Source name:
Universal Human Reference RNA (channel 1) 'D' ODN for 27 hours (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765476
ID:
300765476
12.

'D' ODN + anti-IFNR for 27 hours - repeat 2 - mAdbID:109374

Organism:
Homo sapiens
Source name:
'D' ODN + anti-INFR for 27 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765475
ID:
300765475
13.

Untreated Control - repeat 6 - mAdbID:109029

Organism:
Homo sapiens
Source name:
Untreated Control (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765474
ID:
300765474
14.

'D' ODN for 27 hours- repeat 5 - mAdbID:109027

Organism:
Homo sapiens
Source name:
Universal Human Reference RNA (channel 1) 'D' ODN for 27 hours (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765473
ID:
300765473
15.

'D' ODN + anti-IFNR for 27 hours - repeat 1 - mAdbID:108977

Organism:
Homo sapiens
Source name:
'D' ODN + anti-INFR for 27 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765472
ID:
300765472
16.

'K' ODN + anti-INFR for 9 hours - repeat 2 - mAdbID:108040

Organism:
Homo sapiens
Source name:
'K' ODN + anti-INFR for 9 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765471
ID:
300765471
17.

'K' ODN for 9 hours - repeat 4 - mAdbID:108037

Organism:
Homo sapiens
Source name:
'K' ODN for 9 hours (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765470
ID:
300765470
18.

'K' ODN for 3 hours - repeat 2 - mAdbID:107294

Organism:
Homo sapiens
Source name:
Universal Human Reference RNA (channel 1) 'K' ODN for 3 hours (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765469
ID:
300765469
19.

ODN1612 for 9 hours (K Control)- repeat 1 - mAdbID:105013

Organism:
Homo sapiens
Source name:
ODN1612 for 9 hours (K control) (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765468
ID:
300765468
20.

D122 for 27 hours (D control) - repeat 2 - mAdbID:105012

Organism:
Homo sapiens
Source name:
D122 for 27 hours (D control) (channel 1) Universal Human Reference RNA (channel 2)
Platform:
GPL3779
Series:
GSE30849
Download data: GPR
Sample
Accession:
GSM765467
ID:
300765467
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