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Items: 9

1.

Co-activator function of RIP140 for NFκB/p65-dependent cytokine gene

(Submitter supplied) High- and low-grade inflammatory responses represent a hallmark of numerous pathologies such as sepsis and bacterial infection or insulin resistance and obesity, respectively. Here we describe an unexpected co-activator function of receptor interacting protein (RIP) 140 for nuclear factor (NF) kB, a master transcriptional regulator of inflammation in multiple tissues. Genetic as well as acute deficiency of RIP140, which has been characterized as a co-repressor of various nuclear receptors on metabolic target genes, led to the inhibition of the proinflammatory program in macrophages, mediated by RIP140’s direct impact on cytokine gene promoter activity. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6456
6 Samples
Download data: CEL
Series
Accession:
GSE10386
ID:
200010386
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
3.

Affymetrix GeneChip Mouse Genome 430 2.0 Array [CDF: Mm_UNIGENEG_8]

(Submitter supplied) CDF file was created by Microarray Lab at the Molecular and Behavioral Neuroscience Institute at the University of Michigan. For the CDF file based on Unigene: A probe must hit only one genomic location; Probes that can be mapped to the same target sequence in the correct direction are grouped together in the same probe set;Each probe set must contain at least three oligonucleotide probes and probes in a set are ordered according to their location in the corresponding exon. more...
Organism:
Mus musculus
1 Series
1 Related Platform
6 Samples
Download data: TAR
Platform
Accession:
GPL6456
ID:
100006456
4.

wildtype 3

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262534
ID:
300262534
5.

wildtype 2

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262533
ID:
300262533
6.

wildtype 1

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262532
ID:
300262532
7.

RIP140 knockout 3

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262531
ID:
300262531
8.

RIP140 knockout 2

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262530
ID:
300262530
9.

RIP140 knockout 1

Organism:
Mus musculus
Source name:
bone marrow macrophages
Platform:
GPL6456
Series:
GSE10386
Download data: CEL
Sample
Accession:
GSM262529
ID:
300262529
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