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Transcriptional Profile Analysis of RPGRORF15 frameshift mutation

(Submitter supplied) Purpose: To identify genes and molecular mechanisms associated with disease progression during (7 weeks of age) and after (16 weeks) the peak of photoreceptor death in dogs affected with XLPRA2, a canine model of early-onset XLRP caused by a microdeletion in RPGR exon ORF15. Methods: Expression profiles of diseased and normal dog retinas at both ages were compared using a canine retinal custom cDNA microarray. more...
Organism:
Canis lupus familiaris
Type:
Expression profiling by array
Platform:
GPL9743
12 Samples
Download data: GPR
Series
Accession:
GSE19124
ID:
200019124

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