GSE12817[Accession] - GEO DataSets - NCBI

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Items: 19

Select item 2000128171.

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low, intermediate and high [glucose]

(Submitter supplied) Background: Survival and function of insulin-secreting pancreatic β-cells are markedly altered by changes in nutrient availability. In vitro, culture in 10 rather than 2mM glucose improves rodent β-cell survival and function whereas glucose concentrations above 10mM are deleterious. Aim-Method: To identify the mechanisms of such β-cell plasticity, we tested the effects of a 18h culture at 2, 5, 10 and 30mM glucose on the transcriptome of rat islets precultured for 1 week at 10mM glucose (Affymetrix Rat 230.2 arrays). more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3529
Platform:: GPL1355
16 Samples

Download data: CEL, EXP

Series

Accession:: GSE12817

ID:: 200012817

PubMed Similar studies Analyze with GEO2R

Select item 35292.

Full record GDS3529

Pancreatic islet response to glucose in vitro: dose response

Analysis of pancreatic islets cultured for 18 hours in 2, 5, 10, or 30 mM glucose. Culture in 2 to 10 mM glucose improves beta cell survival and function, while concentrations above 10 mM are deleterious. Results provide insight into the molecular basis of this sensitivity to glucose concentrations.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 4 dose sets

Platform:: GPL1355
Series:: GSE12817
16 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS3529

ID:: 3529

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 1000013553.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:: Rattus norvegicus

107 DataSets
746 Series
13 Related Platforms
23030 Samples

Platform

Accession:: GPL1355

ID:: 100001355

Select item 3003220214.

Pancreatic Islets_18h culture_30 mmol/l glucose_rep4

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 30 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322021

ID:: 300322021

Select item 3003220205.

Pancreatic Islets_18h culture_30 mmol/l glucose_rep3

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 30 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322020

ID:: 300322020

Select item 3003220196.

Pancreatic Islets_18h culture_30 mmol/l glucose_rep2

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 30 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322019

ID:: 300322019

Select item 3003220187.

Pancreatic Islets_18h culture_30 mmol/l glucose_rep1

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 30 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322018

ID:: 300322018

Select item 3003220178.

Pancreatic Islets_18h culture_10 mmol/l glucose_rep4

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 10 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322017

ID:: 300322017

Select item 3003220169.

Pancreatic Islets_18h culture_10 mmol/l glucose_rep3

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 10 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322016

ID:: 300322016

Select item 30032201510.

Pancreatic Islets_18h culture_10 mmol/l glucose_rep2

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 10 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322015

ID:: 300322015

Select item 30032201411.

Pancreatic Islets_18h culture_10 mmol/l glucose_rep1

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 10 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322014

ID:: 300322014

Select item 30032201312.

Pancreatic Islets_18h culture_5 mmol/l glucose_rep4

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 5 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322013

ID:: 300322013

Select item 30032201213.

Pancreatic Islets_18h culture_5 mmol/l glucose_rep3

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 5 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322012

ID:: 300322012

Select item 30032201114.

Pancreatic Islets_18h culture_5 mmol/l glucose_rep2

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 5 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322011

ID:: 300322011

Select item 30032201015.

Pancreatic Islets_18h culture_5 mmol/l glucose_rep1

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 5 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322010

ID:: 300322010

Select item 30032200916.

Pancreatic Islets_18h culture_2 mmol/l glucose_rep4

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 2 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322009

ID:: 300322009

Select item 30032200817.

Pancreatic Islets_18h culture_2 mmol/l glucose_rep3

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 2 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322008

ID:: 300322008

Select item 30032200718.

Pancreatic Islets_18h culture_2 mmol/l glucose_rep2

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 2 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322007

ID:: 300322007

Select item 30032200619.

Pancreatic Islets_18h culture_2 mmol/l glucose_rep1

Organism:: Rattus norvegicus

Source name:: Pancreatic islets, 18h culture, 2 mmol/l glucose

Platform:: GPL1355
Series:: GSE12817
Dataset:: GDS3529

Download data: CEL, EXP

Sample

Accession:: GSM322006

ID:: 300322006

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