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Items: 10

1.

Gene expression from tuft cells under scopolamine treatment

(Submitter supplied) In our study, we investigated the effect of muscarinic receptor blockade on murine intestinal stem cell activity and differentiation. Following pharmacologic (scopolamine) and genetic muscarinic receptor interruption (M3R-KO, M1R-KO; Vil-Cre x M3R fl/fl, Vil-Cre x M1R fl/fl mice, respectively), we observe a selective, significant expansion of DCLK1-positive tuft cells. This is primarily sensed by endocrine Prox1-positive cells (Prox1-CreERT2 x M3R fl/fl mice), while Lgr5-positive ISCs respond with a reduction of their cellular activity (Lgr5-EGFP-IRES-CreERT2 x M3R fl/fl mice). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
8 Samples
Download data: TXT
Series
Accession:
GSE138365
ID:
200138365
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

WH008

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106043
ID:
304106043
4.

WH007

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106042
ID:
304106042
5.

WH006

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106041
ID:
304106041
6.

WH005

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106040
ID:
304106040
7.

WH004

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106039
ID:
304106039
8.

WH003

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106038
ID:
304106038
9.

WH002

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106037
ID:
304106037
10.

WH001

Organism:
Mus musculus
Source name:
tuft_cells
Platform:
GPL24247
Series:
GSE138365
Download data
Sample
Accession:
GSM4106036
ID:
304106036
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Supplemental Content

db=gds|term=GSE138365[Accession]|query=1|qty=2|blobid=MCID_66376941679af6518b8d6803|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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