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Items: 14

1.

Triacylglycerol synthesis enhances macrophage inflammatory function

(Submitter supplied) Macrophages stimulated with lipopolysaccharide (LPS) plus interferon-g (IFNg) accumulate TGs in LDs, and long-chain acylcarnitines. Inhibition of TG synthesis results in diminished LD development, and increased long chain acylcarnitine levels, suggesting that FA fate is balanced between TG and acylcarnitine synthesis. Nevertheless, TG-synthesis is required for inflammatory macrophage function, since its inhibition negatively affects production of proinflammatory IL-1b, IL-6 and PGE2, and phagocytic capacity, and protects against LPS-induced sock in vivo.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21493
12 Samples
Download data: TXT
Series
Accession:
GSE145523
ID:
200145523
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

Stimulated_DGAT1i_M1_18h_3

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS and treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320184
ID:
304320184
4.

Stimulated_DGAT1i_M1_18h_2

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS and treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320183
ID:
304320183
5.

Stimulated_DGAT1i_M1_18h_1

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS and treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320182
ID:
304320182
6.

Resting_DGAT1i_18h_3

Organism:
Mus musculus
Source name:
Resting Macrophages treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320181
ID:
304320181
7.

Resting_DGAT1i_18h_2

Organism:
Mus musculus
Source name:
Resting Macrophages treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320180
ID:
304320180
8.

Resting_DGAT1i_18h_1

Organism:
Mus musculus
Source name:
Resting Macrophages treated with T863
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320179
ID:
304320179
9.

Stimulated_M1_18h_3

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320178
ID:
304320178
10.

Stimulated_M1_18h_2

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320177
ID:
304320177
11.

Stimulated_M1_18h_1

Organism:
Mus musculus
Source name:
Macrophage stimulated with IFNy and LPS
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320176
ID:
304320176
12.

Resting_M0_3

Organism:
Mus musculus
Source name:
Resting Macrophages
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320175
ID:
304320175
13.

Resting_M0_2

Organism:
Mus musculus
Source name:
Resting Macrophages
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320174
ID:
304320174
14.

Resting_M0_1

Organism:
Mus musculus
Source name:
Resting Macrophages
Platform:
GPL21493
Series:
GSE145523
Download data
Sample
Accession:
GSM4320173
ID:
304320173
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Supplemental Content

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