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Items: 8

1.

Targeting steroid receptor co-activator 3 sensitizes myeloma cell to proteasome inhibitor treatment through NSD2-mediated phase separation and chromatin remodeling [ChIP-Seq]

(Submitter supplied) Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key regulatory mode of transcriptional control during cell fate decisions, but the underlying mechanisms are not fully understood. Here we demonstrate that NSD2/SRC-3 complex coordinates histone H3 lysine 36 dimethylation (H3K36me2) and transcriptional elongation factor Pol II to regulate chromatin dynamic and gene transcription during myeloma resistant to bortezomib. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20795
6 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE156870
ID:
200156870
2.

HiSeq X Ten (Homo sapiens)

Platform
Accession:
GPL20795
ID:
100020795
3.

MM.1S BR-SI2-Input

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data
Sample
Accession:
GSM4745859
ID:
304745859
4.

MM.1S BR-Input

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data
Sample
Accession:
GSM4745858
ID:
304745858
5.

MM.1S BR-SI2-Pol II-IP

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4745857
ID:
304745857
6.

MM.1S BR-Pol II-IP

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4745856
ID:
304745856
7.

MM.1S BR-SI2- H3K36me2-IP

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4745855
ID:
304745855
8.

MM.1S BR-H3K36me2-IP

Organism:
Homo sapiens
Source name:
MM.1S
Platform:
GPL20795
Series:
GSE156870 GSE156872
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4745854
ID:
304745854
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Supplemental Content

db=gds|term=GSE156870[Accession]|query=1|qty=2|blobid=MCID_61f0e91c45fc4d46c6704712|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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