GSE172239[Accession] - GEO DataSets - NCBI

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Select item 2001722391.

Gene Expression profile for the characterization of PD-L1 blockade in melanoma model

(Submitter supplied) Only a subset of patients responds to immune checkpoint blockade in melanoma. A preclinical model recapitulating the clinical activity of ICB would provide a valuable platform for mechanistic studies. We used melanoma tumors arising from an Hgftg;Cdk4R24C/R24C genetically engineered mouse (GEM) model to evaluate the efficacy of an anti-mouse PD-L1 antibody similar to the anti-human PD-L1 antibodies durvalumab and atezolizumab. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
90 Samples

Download data: CEL

Series

Accession:: GSE172239

ID:: 200172239

Analyze with GEO2R

Select item 1000012612.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:: Mus musculus

601 DataSets
4538 Series
40 Related Platforms
58877 Samples

Platform

Accession:: GPL1261

ID:: 100001261

Select item 3052446783.

PBS 10ml/Kg [189749]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244678

ID:: 305244678

Select item 3052446774.

PBS 10ml/Kg [189748]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244677

ID:: 305244677

Select item 3052446765.

PBS 10ml/Kg [189747]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244676

ID:: 305244676

Select item 3052446756.

PBS 10ml/Kg [189746]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244675

ID:: 305244675

Select item 3052446747.

Relapse to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197463]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244674

ID:: 305244674

Select item 3052446738.

Relapse to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197461]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244673

ID:: 305244673

Select item 3052446729.

Relapse to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197446]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244672

ID:: 305244672

Select item 30524467110.

Stabilization to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197454]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244671

ID:: 305244671

Select item 30524467011.

Stabilization to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197456]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244670

ID:: 305244670

Select item 30524466912.

Stabilization to 10mg/kg anti-mouse PD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197442]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244669

ID:: 305244669

Select item 30524466813.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197409]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244668

ID:: 305244668

Select item 30524466714.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197436]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244667

ID:: 305244667

Select item 30524466615.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197429]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244666

ID:: 305244666

Select item 30524466516.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197434]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244665

ID:: 305244665

Select item 30524466417.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197444]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244664

ID:: 305244664

Select item 30524466318.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197441]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244663

ID:: 305244663

Select item 30524466219.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197437]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244662

ID:: 305244662

Select item 30524466120.

Non-responders to 10mg/kg anti-mousePD-L1 mIgG1 D265A (clone 80; AstraZeneca Cat# AB740080, Batch# SP15-221) [197404]

Organism:: Mus musculus

Source name:: Subcutaneous tumor

Platform:: GPL1261
Series:: GSE172239

Download data: CEL

Sample

Accession:: GSM5244661

ID:: 305244661

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