GEO DataSets

(Submitter supplied) Heart formation requires the fusion of bilateral cardiomyocyte populations as they move toward the embryonic midline. The bHLH transcription factor Hand2 is essential for cardiac fusion; however, the effector genes that execute this function of Hand2 are unknown. Here, we provide the first evidence for a downstream component of the Hand2 pathway that mediates cardiac morphogenesis. Although hand2 is expressed in cardiomyocytes, mosaic analysis demonstrates that hand2 plays a non-autonomous role in regulating cardiomyocyte movement. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Dataset:

GDS3735

Platform:

GPL1319

6 Samples

Download data: CEL

Analysis of Hand2 mutant embryo hearts at 19 hpf. Hand2 is a myocardial transcription factor essential for fusion of bilateral cardiomyocyte populations moving toward the embryonic midline. Results provide insight into downstream components of the Hand2 pathway that mediates cardiac morphogenesis.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE23381

6 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html The Affymetrix GeneChip Zebrafish Genome Array can be used to study gene expression of over 14,900 Danio rerio transcripts. Sequence information for this array was selected from the following public data sources: RefSeq (July 2003), GenBank (release 136.0, June 2003), dbEST (July 2003), and UniGene (Build 54, June 2003). more...

Organism:

Danio rerio

18 DataSets

135 Series

1 Related Platform

1713 Samples

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