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Items: 13

1.

Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia

(Submitter supplied) Microglia are the resident mononuclear phagocytes of the CNS parenchyma and represent an initial line of defense against invading microorganisms. Microglia utilize Toll-like receptors (TLRs) for pathogen recognition and TLR2 specifically senses conserved motifs of gram-positive bacteria including lipoproteins, lipoteichoic acids, and peptidoglycan (PGN) leading to cytokine/chemokine production. Interestingly, primary microglia derived from TLR2 knockout (KO) mice over-expressed numerous IL-12 family members, including IL-12p40, IL-12p70, and IL-27 in response to intact S. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
11 Samples
Download data: TXT
Series
Accession:
GSE24935
ID:
200024935

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
902 Series
16886 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885

3.

TLR2_KO+SA_12_HR-3

Organism:
Mus musculus
Source name:
microglia, TLR2 KO, 12hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612975
ID:
300612975

4.

TLR2_KO+SA_12_HR-1

Organism:
Mus musculus
Source name:
microglia, TLR2 KO, 12hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612974
ID:
300612974

5.

TLR2_KO+SA_6_HR-3

Organism:
Mus musculus
Source name:
microglia, TLR2 KO, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612973
ID:
300612973

6.

TLR2_KO+SA_6_HR-2

Organism:
Mus musculus
Source name:
microglia, TLR2 KO, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612972
ID:
300612972

7.

TLR2_KO+SA_6_HR-1

Organism:
Mus musculus
Source name:
microglia, TLR2 KO, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612971
ID:
300612971

8.

WT-SA_12_HR-3

Organism:
Mus musculus
Source name:
microglia, wild type control, 12hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612970
ID:
300612970

9.

WT-SA_12_HR-2

Organism:
Mus musculus
Source name:
microglia, wild type control, 12hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612969
ID:
300612969

10.

WT-SA_12_HR-1

Organism:
Mus musculus
Source name:
microglia, wild type control, 12hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612968
ID:
300612968

11.

WT-SA_6_HR-3

Organism:
Mus musculus
Source name:
microglia, wild type control, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612967
ID:
300612967

12.

WT-SA_6_HR-2

Organism:
Mus musculus
Source name:
microglia, wild type control, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612966
ID:
300612966

13.

WT-SA_6_HR-1

Organism:
Mus musculus
Source name:
microglia, wild type control, 6hr
Platform:
GPL6885
Series:
GSE24935
Download data
Sample
Accession:
GSM612965
ID:
300612965

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