GSE30651[Accession] - GEO DataSets - NCBI

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Items: 18

Select item 2000306511.

Conditional elimination of c-Met signaling in the liver aggravates oxidative stress and cholestasis, and deregulates lipid metabolism, under a high cholesterol diet

(Submitter supplied) Background: Genetic elimination of c-Met signaling in the liver has been shown to impact many cellular pathways involved in repair, regeneration, lipid homeostasis and redox balance. In this study, we analyzed a nutritional model of hepatic steatosis in Met fl/fl ; Alb-Cre +/- (MetKO) mice in a 129SV/C57BL/6 background fed a high cholesterol diet for 30 days. Methods: Liver injury was determined by histopathology and plasma enzymes, transcriptomic changes were examined using gene expression microarrays, and evaluation of key molecules involved in liver damage and lipid homestasis were evaluated by Western blot analysis. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
16 Samples

Download data: TXT

Series

Accession:: GSE30651

ID:: 200030651

Analyze with GEO2R

Select item 1000068852.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...

Organism:: Mus musculus

33 DataSets
902 Series
16886 Samples

Download data: BGX

Platform

Accession:: GPL6885

ID:: 100006885

Select item 3007599643.

High Cholesterol Diet, c-Met KO mice, rep4

Organism:: Mus musculus

Source name:: liver, c-Met KO, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759964

ID:: 300759964

Select item 3007599634.

High Cholesterol Diet, c-Met KO mice, rep3

Organism:: Mus musculus

Source name:: liver, c-Met KO, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759963

ID:: 300759963

Select item 3007599625.

High Cholesterol Diet, c-Met KO mice, rep2

Organism:: Mus musculus

Source name:: liver, c-Met KO, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759962

ID:: 300759962

Select item 3007599616.

High Cholesterol Diet, c-Met KO mice, rep1

Organism:: Mus musculus

Source name:: liver, c-Met KO, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759961

ID:: 300759961

Select item 3007599607.

High Cholesterol Diet, WT mice, rep4

Organism:: Mus musculus

Source name:: liver, WT, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759960

ID:: 300759960

Select item 3007599598.

High Cholesterol Diet, WT mice, rep3

Organism:: Mus musculus

Source name:: liver, WT, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759959

ID:: 300759959

Select item 3007599589.

High Cholesterol Diet, WT mice, rep2

Organism:: Mus musculus

Source name:: liver, WT, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759958

ID:: 300759958

Select item 30075995710.

High Cholesterol Diet, WT mice, rep1

Organism:: Mus musculus

Source name:: liver, WT, high cholesterol diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759957

ID:: 300759957

Select item 30075995611.

Chow Diet, c-Met KO mice, rep4

Organism:: Mus musculus

Source name:: liver, c-Met KO, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759956

ID:: 300759956

Select item 30075995512.

Chow Diet, c-Met KO mice, rep3

Organism:: Mus musculus

Source name:: liver, c-Met KO, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759955

ID:: 300759955

Select item 30075995413.

Chow Diet, c-Met KO mice, rep2

Organism:: Mus musculus

Source name:: liver, c-Met KO, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759954

ID:: 300759954

Select item 30075995314.

Chow Diet, c-Met KO mice, rep1

Organism:: Mus musculus

Source name:: liver, c-Met KO, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759953

ID:: 300759953

Select item 30075995215.

Chow Diet, WT mice, rep4

Organism:: Mus musculus

Source name:: liver, WT, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759952

ID:: 300759952

Select item 30075995116.

Chow Diet, WT mice, rep3

Organism:: Mus musculus

Source name:: liver, WT, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759951

ID:: 300759951

Select item 30075995017.

Chow Diet, WT mice, rep2

Organism:: Mus musculus

Source name:: liver, WT, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759950

ID:: 300759950

Select item 30075994918.

Chow Diet, WT mice, rep1

Organism:: Mus musculus

Source name:: liver, WT, control diet

Platform:: GPL6885
Series:: GSE30651

Sample

Accession:: GSM759949

ID:: 300759949

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