GSE32473[Accession] - GEO DataSets - NCBI

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Select item 2000324731.

Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis.

(Submitter supplied) Topical corticosteroids and calcineurin inhibitors are well known treatments of atopic dermatitis (AD), but differ in their efficacy and side effects. A study in AD patients has demonstrated that betamethasone valerate (BM) though clinically more efficient impaired skin barrier repair in contrast to pimecrolimus. Objective: The present study elucidates the mode of action of topical BM and pimecrolimus cream in AD. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4460
Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE32473

ID:: 200032473

PubMed Similar studies Analyze with GEO2R

Select item 44602.

Full record GDS4460

Pimecrolimus and betamethasone valerate effects on lesional skin of actopic dermatitis

Analysis of skin biopsies from AD patients treated with pimecrolimus on 1 upper limb and betamethasone (BM) on the other upper limb. BM is clinically more effective but does not restore the skin barrier, compared to pimecrolimus. Results provide insight into mechanisms of action of both substances.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 9 disease state, 3 protocol sets

Platform:: GPL570
Series:: GSE32473
30 Samples

Download data: CEL

DataSet

Accession:: GDS4460

ID:: 4460

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:: Homo sapiens

602 DataSets
5643 Series
61 Related Platforms
171150 Samples

Platform

Accession:: GPL570

ID:: 100000570

Select item 3008036144.

patient 16, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 16, right arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803614

ID:: 300803614

Select item 3008036135.

patient 16, baseline

Organism:: Homo sapiens

Source name:: patient 16, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803613

ID:: 300803613

Select item 3008036126.

patient 16, arm treated with betamethasone

Organism:: Homo sapiens

Source name:: patient 16, left arm treated with betamethasone until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803612

ID:: 300803612

Select item 3008036117.

patient 15, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 15, right arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803611

ID:: 300803611

Select item 3008036108.

patient 15, baseline

Organism:: Homo sapiens

Source name:: patient 15, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803610

ID:: 300803610

Select item 3008036099.

patient 15, arm treated with betamethasone

Organism:: Homo sapiens

Source name:: patient 15, left arm treated with betamethasone until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803609

ID:: 300803609

Select item 30080360810.

patient 14, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 14, right arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803608

ID:: 300803608

Select item 30080360711.

patient 14, baseline

Organism:: Homo sapiens

Source name:: patient 14, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803607

ID:: 300803607

Select item 30080360612.

patient 14, arm treated with betamethasone

Organism:: Homo sapiens

Source name:: patient 14, left arm treated with betamethasone until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803606

ID:: 300803606

Select item 30080360513.

patient 13, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 13, right arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803605

ID:: 300803605

Select item 30080360414.

patient 13, baseline

Organism:: Homo sapiens

Source name:: patient 13, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803604

ID:: 300803604

Select item 30080360315.

patient 13, arm treated with betamethasone

Organism:: Homo sapiens

Source name:: patient 13, left arm treated with betamethasone until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803603

ID:: 300803603

Select item 30080360216.

patient 12, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 12, left arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803602

ID:: 300803602

Select item 30080360117.

patient 12, baseline

Organism:: Homo sapiens

Source name:: patient 12, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803601

ID:: 300803601

Select item 30080360018.

patient 12, arm treated with betamethasone

Organism:: Homo sapiens

Source name:: patient 12, right arm treated with betamethasone until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803600

ID:: 300803600

Select item 30080359919.

patient 11, arm treated with pimecrolimus

Organism:: Homo sapiens

Source name:: patient 11, left arm treated with pimecrolimus until day 22

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803599

ID:: 300803599

Select item 30080359820.

patient 11, baseline

Organism:: Homo sapiens

Source name:: patient 11, baseline

Platform:: GPL570
Series:: GSE32473
Dataset:: GDS4460

Download data: CEL

Sample

Accession:: GSM803598

ID:: 300803598

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