GSE37618[Accession] - GEO DataSets - NCBI

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Select item 2000376181.

Glucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations with Aging

(Submitter supplied) Although glucocorticoids (GCs) are known to exert numerous effects in the hippocampus, their chronic regulatory functions remain poorly understood. Moreover, evidence is inconsistent regarding the longstanding hypothesis that chronic GC exposure promotes brain aging/Alzheimer's disease. Here, we adrenalectomized male F344 rats at 15-months-of-age, maintained them for 3 months with implanted corticosterone (CORT) pellets producing low or intermediate (glucocorticoid-receptor (GR)-activating) blood levels of CORT, and performed microarray/pathway analyses in hippocampal CA1. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4757
Platform:: GPL85
39 Samples

Download data: CEL

Series

Accession:: GSE37618

ID:: 200037618

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 47572.

Full record GDS4757

Corticosterone effect on hippocampus: dose response

Analysis of hippocampal CA1 from adrenalectomized F344 males maintained for 3 months with implanted corticosterone (CORT) pellets to produce low or intermediate (glucocorticoid receptor-activating) blood levels of CORT. Results provide insight into the effects of chronic CORT on the hippocampus.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 4 agent, 4 dose, 2 protocol sets

Platform:: GPL85
Series:: GSE37618
39 Samples

Download data: CEL

DataSet

Accession:: GDS4757

ID:: 4757

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000000853.

[RG_U34A] Affymetrix Rat Genome U34 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The RG-U34 set includes 3 arrays with a total of 26379 entries and was indexed 29-Jan-2002. more...

Organism:: Rattus norvegicus

98 DataSets
174 Series
1 Related Platform
3495 Samples

Platform

Accession:: GPL85

ID:: 100000085

Select item 3009233274.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 39

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923327

ID:: 300923327

Select item 3009233265.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 38

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923326

ID:: 300923326

Select item 3009233256.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 37

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923325

ID:: 300923325

Select item 3009233247.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 36

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923324

ID:: 300923324

Select item 3009233238.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 35

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923323

ID:: 300923323

Select item 3009233229.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 34

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923322

ID:: 300923322

Select item 30092332110.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 33

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923321

ID:: 300923321

Select item 30092332011.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 32

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923320

ID:: 300923320

Select item 30092331912.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 31

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923319

ID:: 300923319

Select item 30092331813.

rat hippocampus (CA1 region), LowInj, 18 months old, subject 30

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowInj

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923318

ID:: 300923318

Select item 30092331714.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 29

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923317

ID:: 300923317

Select item 30092331615.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 28

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923316

ID:: 300923316

Select item 30092331516.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 27

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923315

ID:: 300923315

Select item 30092331417.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 26

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923314

ID:: 300923314

Select item 30092331318.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 25

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923313

ID:: 300923313

Select item 30092331219.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 24

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923312

ID:: 300923312

Select item 30092331120.

rat hippocampus (CA1 region), LowCort, 18 months old, subject 23

Organism:: Rattus norvegicus

Source name:: rat hippocampus (CA1 region)_LowCort

Platform:: GPL85
Series:: GSE37618
Dataset:: GDS4757

Download data: CEL

Sample

Accession:: GSM923311

ID:: 300923311

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