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Items: 15

1.

Regulatory role of multinucleated giant cells derived from placental CD14+ macrophages: Pathophysiological implications

(Submitter supplied) The role of placental macrophages is largely ignored in the success of pregnancy. We found that CD14+ macrophages purified from at-term placentas spontaneously matured into multinucleated giant cells (MGCs). MGCs lost the expression of CD14 and co-inhibitory molecules, such as Programmed cell Death-Ligands 1 and 2. Although MGCs kept phagocytosis and property to produce ROS, their inflammatory potential measured by TNF/IL-10 imbalance and activation of p38 MAPK and NF-κB was blunted without being associated with M2 phenotype. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5314
Platform:
GPL6480
12 Samples
Download data: TXT
Series
Accession:
GSE38747
ID:
200038747
2.
Full record GDS5314

Placental CD14+ macrophage-derived multinucleated giant cells

Analysis of placental multinucleated giant cells (MGCs) obtained from at-term placental CD14+ macrophages cultured in DMEM-F12 containing 10% FCS and antibiotics for 9 days. Results provide insight into molecular mechanisms underlying the maturation of macrophages into MGCs.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell type sets
Platform:
GPL6480
Series:
GSE38747
12 Samples
Download data: TXT
DataSet
Accession:
GDS5314
ID:
5314
3.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
21 DataSets
911 Series
4 Related Platforms
24196 Samples
Download data
Platform
Accession:
GPL6480
ID:
100006480
4.

MGC_Placenta1_rep3

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948997
ID:
300948997
5.

MGC_Placenta2_rep3

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948996
ID:
300948996
6.

CD14_Placenta2_rep4

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948995
ID:
300948995
7.

CD14_Placenta2_rep3

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948994
ID:
300948994
8.

CD14_Placenta1_rep2

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948993
ID:
300948993
9.

MGC_Placenta1_rep2

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948992
ID:
300948992
10.

CD14_Placenta2_rep2

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948991
ID:
300948991
11.

CD14_Placenta1_rep1

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948990
ID:
300948990
12.

MGC_Placenta2_rep2

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948989
ID:
300948989
13.

MGC_Placenta2_rep1

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948988
ID:
300948988
14.

CD14_Placenta2_rep1

Organism:
Homo sapiens
Source name:
CD14
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948987
ID:
300948987
15.

MGC_Placenta1_rep1

Organism:
Homo sapiens
Source name:
MGC
Platform:
GPL6480
Series:
GSE38747
Dataset:
GDS5314
Download data: TXT
Sample
Accession:
GSM948986
ID:
300948986
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