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Items: 8

1.

Transcriptional profiling analysis of pre-selected DP thymocytes in response to positive and negative selection signals

(Submitter supplied) Sustained Ca2+ entry into CD4+CD8+ double-positive thymocytes is required for positive selection. We identified a voltage-gated Na+ channel (VGSC), essential for positive selection of CD4+ T cells. Pharmacological inhibition of VGSC activity inhibited sustained Ca2+ influx induced by positive-selecting ligands and in vitro positive selection of CD4+ but not CD8+ T cells. In vivo shRNA knockdown of Scn5a specifically inhibited positive selection of CD4+ T cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
6 Samples
Download data: TXT
Series
Accession:
GSE38909
ID:
200038909
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
881 Series
16514 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

AND.Rag1-/-H-2d DP thymocytes_Hb/I-Ek stimulation_rep2

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952013
ID:
300952013
4.

AND.Rag1-/-H-2d DP thymocytes_gp250/I-Ek stimulation_rep2

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952012
ID:
300952012
5.

AND.Rag1-/-H-2d DP thymocytes_MCC/I-Ek stimulation_rep2

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952011
ID:
300952011
6.

AND.Rag1-/-H-2d DP thymocytes_Hb/I-Ek stimulation_rep1

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952010
ID:
300952010
7.

AND.Rag1-/-H-2d DP thymocytes_gp250/I-Ek stimulation_rep1

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952009
ID:
300952009
8.

AND.Rag1-/-H-2d DP thymocytes_MCC/I-Ek stimulation_rep1

Organism:
Mus musculus
Source name:
Pre-selected DP thymocytes from AND.Rag1-/-H-2d mouse
Platform:
GPL6885
Series:
GSE38909
Download data
Sample
Accession:
GSM952008
ID:
300952008
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Supplemental Content

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