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Items: 13

1.

Basonuclin: A novel mammalian maternal effect gene

(Submitter supplied) Basonuclin, which is a zinc-finger protein found in abundance only in the keratinocytes of the stratified epithelium, male germ cells and oocytes, qualifies as a maternal-effect gene because the source of pre-implantation embryonic basonuclin is maternal. Using a transgenic-RNAi approach, we knocked-down basonuclin specifically in mouse oocytes, which led to female sub-fertility. Basonuclin deficiency in oocytes perturbed both RNA polymerase I- and II-mediated transcription and oocyte morphology was affected as evidenced by cytoplasmic and cell surface abnormalities. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1978
Platform:
GPL1261
10 Samples
Download data
Series
Accession:
GSE4029
ID:
200004029
2.
Full record GDS1978

Zinc-finger protein basonuclin knockdown effect on oocytes

Analysis of oocytes following RNAi knockdown of basonuclin (Bnc1), a zinc-finger protein found in abundance in oocytes. The Bnc1 gene qualifies as a maternal-effect gene because the source of pre-implantation embryonic Bnc1 is maternal. Results provide insight into the function of Bnc1.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL1261
Series:
GSE4029
10 Samples
Download data
DataSet
Accession:
GDS1978
ID:
1978
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4424 Series
40 Related Platforms
57658 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

RNAi -Transgenic replicate 13

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92230
ID:
300092230
5.

RNAi -Transgenic replicate 12

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92229
ID:
300092229
6.

RNAi -Transgenic replicate 11

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92228
ID:
300092228
7.

RNAi -Transgenic replicate 6

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92227
ID:
300092227
8.

RNAi -Transgenic replicate 5

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92226
ID:
300092226
9.

RNAi -Transgenic replicate 4

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92225
ID:
300092225
10.

Non-Transgenic replicate 8

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92224
ID:
300092224
11.

Non -Transgenic replicate 7

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92223
ID:
300092223
12.

Non-Transgenic replicate 2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92222
ID:
300092222
13.

Non-Transgenic replicate 1

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL1261
Series:
GSE4029
Dataset:
GDS1978
Download data
Sample
Accession:
GSM92221
ID:
300092221
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