GSE4585[Accession] - GEO DataSets

Select item 2000045851.

The zebrafish runzel mutant results in a novel muscular dystrophy phenotype due to a titin mutation

(Submitter supplied) The zebrafish runzel (ruz) carries a mutation in the titin gene resulting in muscle degeneration and embryonic lethality. At the onset of the visible phenotype (3-3.5 days post fertilization), RNA expression of the tail and trunk (primarily skeletal muscle) was compared between ruz mutants and wildtype siblings using the Affymetrix Zebrafish Gene Chip. Mutant RNA was matched with RNA of wildtype siblings from the same clutch. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Dataset:: GDS2192
Platform:: GPL1319
6 Samples

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Series

Accession:: GSE4585

ID:: 200004585

Analyze with GEO2R

Select item 21922.

Titin mutation effect on embryonic muscles

Analysis of trunk and tail muscles of runzel (ruz) mutant embryos at 3.5 days post fertilization (dpf). Ruz mutants carry a mutation in the titin gene resulting in muscle degeneration and embryonic lethality. Results provide insight into the pathogenesis of titin muscular dystrophy.

Organism:: Danio rerio

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1319
Series:: GSE4585
6 Samples

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DataSet

Accession:: GDS2192

ID:: 2192

GEO Profiles Analyze DataSet

Select item 1000013193.

[Zebrafish] Affymetrix Zebrafish Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html The Affymetrix GeneChip Zebrafish Genome Array can be used to study gene expression of over 14,900 Danio rerio transcripts. Sequence information for this array was selected from the following public data sources: RefSeq (July 2003), GenBank (release 136.0, June 2003), dbEST (July 2003), and UniGene (Build 54, June 2003). more...