GSE47548[Accession] - GEO DataSets - NCBI

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Select item 2000475481.

Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration

(Submitter supplied) Scnn1b-Tg mice overexpress the beta subunit of the epithelial sodium channel (Scnn1b) in airway Club cells. The general phenotype of these mice is described in three published manuscripts (Mall et al. 2004, Nature Medicine, 10(5):487-93; Mall et al. 2008, Am J Respir Crit Care Med. 177(7):730-42; and Livraghi-Butrico et al. 2012, Physiol. Genomics 44(8):470-84. Briefly, overexpression of the Scnn1b transgene in airway Club cells leads to hyperabsorption of sodium from the airway surface liquid, dehydrated airway surface liquid and mucus, and reduced mucus clearance associated with accumulation of mucus plugs/plaques. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11533
36 Samples

Download data: CEL

Series

Accession:: GSE47548

ID:: 200047548

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000115332.

[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html MoGene-1_1-st-v1.na31.mm9.transcript.csv #%create_date=Fri Aug 27 17:50:02 2010 PDT #%chip_type=MoGene-1_1-st-v1 #%lib_set_name=MoGene-1_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm8 #%genome-lifted_from-version-ncbi=36 #%netaffx-annotation-date=2010-07-15 #%netaffx-annotation-netaffx-build=31 Protocol: see manufacturer's web site

Organism:: Mus musculus

10 DataSets
173 Series
7 Related Platforms
4209 Samples

Platform

Accession:: GPL11533

ID:: 100011533

Select item 3011522643.

Purified lung lavage macrophages Scnn1b-Tg, PND 42 germ-free, biological replicate 3

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, germ-free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152264

ID:: 301152264

Select item 3011522634.

Purified lung lavage macrophages Scnn1b-Tg, PND 42 germ-free, biological replicate 2

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, germ-free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152263

ID:: 301152263

Select item 3011522625.

Purified lung lavage macrophages Scnn1b-Tg, PND 42 germ-free, biological replicate 1

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, germ-free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152262

ID:: 301152262

Select item 3011522616.

Purified lung lavage macrophages WT, PND 42 germ-free, biological replicate 3

Organism:: Mus musculus

Source name:: Wildtype, macrophages, germ-free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152261

ID:: 301152261

Select item 3011522607.

Purified lung lavage macrophages WT, PND 42 germ-free, biological replicate 2

Organism:: Mus musculus

Source name:: Wildtype, macrophages, germ-free free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152260

ID:: 301152260

Select item 3011522598.

Purified lung lavage macrophages WT, PND 42 germ-free, biological replicate 1

Organism:: Mus musculus

Source name:: Wildtype, macrophages, germ-free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152259

ID:: 301152259

Select item 3011522589.

Purified lung lavage macrophages Scnn1b-Tg, PND 42, biological replicate 4

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152258

ID:: 301152258

Select item 30115225710.

Purified lung lavage macrophages Scnn1b-Tg, PND 42, biological replicate 3

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152257

ID:: 301152257

Select item 30115225611.

Purified lung lavage macrophages Scnn1b-Tg, PND 42, biological replicate 2

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152256

ID:: 301152256

Select item 30115225512.

Purified lung lavage macrophages Scnn1b-Tg, PND 42, biological replicate 1

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152255

ID:: 301152255

Select item 30115225413.

Purified lung lavage macrophages Scnn1b-Tg, PND 10, biological replicate 4

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152254

ID:: 301152254

Select item 30115225314.

Purified lung lavage macrophages Scnn1b-Tg, PND 10, biological replicate 3

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152253

ID:: 301152253

Select item 30115225215.

Purified lung lavage macrophages Scnn1b-Tg, PND 10, biological replicate 2

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152252

ID:: 301152252

Select item 30115225116.

Purified lung lavage macrophages Scnn1b-Tg, PND 10, biological replicate 1

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152251

ID:: 301152251

Select item 30115225017.

Purified lung lavage macrophages Scnn1b-Tg, PND 3, biological replicate 4

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152250

ID:: 301152250

Select item 30115224918.

Purified lung lavage macrophages Scnn1b-Tg, PND 3, biological replicate 3

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152249

ID:: 301152249

Select item 30115224819.

Purified lung lavage macrophages Scnn1b-Tg, PND 3, biological replicate 2

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152248

ID:: 301152248

Select item 30115224720.

Purified lung lavage macrophages Scnn1b-Tg, PND 3, biological replicate 1

Organism:: Mus musculus

Source name:: Scnn1b-Tg, macrophages, specific pathogene free facility

Platform:: GPL11533
Series:: GSE47548 GSE47551

Download data: CEL

Sample

Accession:: GSM1152247

ID:: 301152247

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