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Items: 1 to 20 of 21

1.

Global analysis of transcriptional changes following genomic demethylation in chondrocytes, osteoblasts, and fibroblasts

(Submitter supplied) DNA methylation can contribute to the stable transcriptional silencing of mammalian genes. Oftentimes, these genes are important developmental regulators, and their silencing in cell types where they are not supposed to be active is important for the phenotypic stability of the cells. To identify key developmental regulator genes whose expression in terminally differentiated cells may be inhibited by DNA methylation, mouse dermal fibroblasts were demethylated with 5-aza-2’-deoxycytidine, and changes in gene expression monitored by microarray analysis. more...
Organism:
Mus musculus
Type:
Expression profiling by array; Methylation profiling by array
Dataset:
GDS2091
Platform:
GPL1261
18 Samples
Download data
Series
Accession:
GSE4768
ID:
200004768

Analyze with GEO2R

2.
Full record GDS2091

DNA demethylation effect on terminally differentiated cells

Analysis of chondrocytes, fibroblasts, and osteoblasts treated with the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-2dC). DNA methylation contributes to transcriptional silencing. Results identify genes whose expression is inhibited by DNA methylation in terminally differentiated cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 3 cell type sets
Platform:
GPL1261
Series:
GSE4768
18 Samples
Download data
DataSet
Accession:
GDS2091
ID:
2091

GEO Profiles Analyze DataSet

3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4538 Series
40 Related Platforms
58877 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261

4.

chondrocyte_5azatreated_rep3

Organism:
Mus musculus
Source name:
primary chondrocytes treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107805
ID:
300107805

5.

chondrocyte_5azatreated_rep2

Organism:
Mus musculus
Source name:
primary chondrocytes treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107804
ID:
300107804

6.

chondrocyte_5azatreated_rep1

Organism:
Mus musculus
Source name:
primary chondrocytes treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107803
ID:
300107803

7.

chondrocyte_control_rep3

Organism:
Mus musculus
Source name:
primary chondrocytes untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107802
ID:
300107802

8.

Chondrocyte_control_rep2

Organism:
Mus musculus
Source name:
primary chondrocytes untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107801
ID:
300107801

9.

chondrocyte_control_rep1

Organism:
Mus musculus
Source name:
primary chondrocytes untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107800
ID:
300107800

10.

osteoblast_control_rep3

Organism:
Mus musculus
Source name:
primary osteoblasts untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107799
ID:
300107799

11.

osteoblast_control_rep2

Organism:
Mus musculus
Source name:
primary osteoblasts untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107798
ID:
300107798

12.

osteoblast_control_rep1

Organism:
Mus musculus
Source name:
primary osteoblasts untreated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107797
ID:
300107797

13.

osteoblast_5azatreated_rep3

Organism:
Mus musculus
Source name:
primary osteoblasts treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107796
ID:
300107796

14.

osteoblast_5azatreated_rep2

Organism:
Mus musculus
Source name:
primary osteoblasts treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107795
ID:
300107795

15.

osteoblast_5azatreated_rep1

Organism:
Mus musculus
Source name:
primary osteoblasts treated
Platform:
GPL1261
Series:
GSE4768
Dataset:
GDS2091
Download data
Sample
Accession:
GSM107794
ID:
300107794

16.

fibroblast_5azacontrol_rep3

Organism:
Mus musculus
Source name:
primary dermal fibroblasts untreated
Platform:
GPL1261
Series:
GSE4696 GSE4768
Datasets:
GDS2044 GDS2091
Download data
Sample
Accession:
GSM106156
ID:
300106156

17.

fibroblast_5azatreated_rep3

Organism:
Mus musculus
Source name:
primary dermal fibroblasts treated
Platform:
GPL1261
Series:
GSE4696 GSE4768
Datasets:
GDS2044 GDS2091
Download data
Sample
Accession:
GSM106155
ID:
300106155

18.

fibroblast_5azacontrol_rep2

Organism:
Mus musculus
Source name:
primary dermal fibroblasts untreated
Platform:
GPL1261
Series:
GSE4696 GSE4768
Datasets:
GDS2044 GDS2091
Download data
Sample
Accession:
GSM106154
ID:
300106154

19.

fibroblast_5azatreated_rep2

Organism:
Mus musculus
Source name:
primary dermal fibroblasts treated
Platform:
GPL1261
Series:
GSE4696 GSE4768
Datasets:
GDS2044 GDS2091
Download data
Sample
Accession:
GSM106153
ID:
300106153

20.

fibroblast_5azacontrol_rep1

Organism:
Mus musculus
Source name:
primary dermal fibroblasts untreated
Platform:
GPL1261
Series:
GSE4696 GSE4768
Datasets:
GDS2044 GDS2091
Download data
Sample
Accession:
GSM106152
ID:
300106152

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