GSE48443[Accession] - GEO DataSets

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Items: 10

Select item 2000484431.

Knockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis.

(Submitter supplied) Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of paracellular permeability to ions and solutes. Claudin-18, a member of the large claudin family, is highly expressed in lung epithelium. To elucidate the role of claudin-18 in alveolar epithelial barrier function and fluid homeostasis, we generated claudin-18 knockout (C18 KO) mice. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4961
Platform:: GPL6885
7 Samples

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Series

Accession:: GSE48443

ID:: 200048443

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49612.

Claudin 18 deficiency effect on the lung

Analysis of lungs of claudin 18 (C18) mutants. Claudin are constituents of epithelial and endothelial tight junctions that regulate paracellular permeability to ions and solutes. C18 is expressed in the lung alveolar epthelia (AE). Results provide insight into the role of C18 in AE barrier function.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6885
Series:: GSE48443
7 Samples

Download data

DataSet

Accession:: GDS4961

ID:: 4961

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000068853.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...