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Items: 1 to 20 of 27

1.

Gene expression profiling of liver tissue from lean (WT) and obese (ob/ob) mice following a chronic exposure of low doses of pharmaceuticals

(Submitter supplied) BACKGOUND: Drinking water can be contaminated with pharmaceuticals. However, it is uncertain whether this contamination can have harmful consequences for the liver, especially in the context of obesity. OBJECTIVES: To determine whether chronic, low dose exposure to pharmaceuticals could have deleterious effects in livers of lean and obese mice. METHODS: Lean and ob/ob male mice (5-week-old) were treated for 4 months with a mixture of 11 drugs (acetaminophen, caffeine, carbamazepine, cotinine, diclofenac, erythromycin, ibuprofen, phenazone, roxithromycin, salicylic acid and sulfamethoxazole) provided in drinking water at a concentration of 1 mg/L (for each drug). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5258
Platform:
GPL7202
24 Samples
Download data: TXT
Series
Accession:
GSE49195
ID:
200049195

PubMed Similar studies Analyze with GEO2R

2.
Full record GDS5258

Chronic, low level drug exposure effect on obese liver

Analysis of liver from ob/ob obese males given water with 1 mg/L each of 11 drugs during 4 months. Contamination of drinking water with these drugs may have harmful effects on health. Results provide insight into mechanisms underlying obese liver responses to water-borne drug contamination.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL7202
Series:
GSE49195
24 Samples
Download data: TXT
DataSet
Accession:
GDS5258
ID:
5258

PubMed Similar studies GEO Profiles Analyze DataSet

3.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...
Organism:
Mus musculus
16 DataSets
653 Series
1 Related Platform
10672 Samples
Download data
Platform
Accession:
GPL7202
ID:
100007202

4.

ob/ob_1mg/L_mouse#6

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #6
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195305
ID:
301195305

5.

ob/ob_1mg/L_mouse#5

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #5
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195304
ID:
301195304

6.

ob/ob_1mg/L_mouse#4

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #4
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195303
ID:
301195303

7.

ob/ob_1mg/L_mouse#3

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #3
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195302
ID:
301195302

8.

ob/ob_1mg/L_mouse#2

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #2
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195301
ID:
301195301

9.

ob/ob_1mg/L_mouse#1

Organism:
Mus musculus
Source name:
liver tissue from treated ob/ob animal (1mg/L), mouse/replicate #1
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195300
ID:
301195300

10.

lean_1mg/L_mouse#6

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #6
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195299
ID:
301195299

11.

lean_1mg/L_mouse#5

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #5
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195298
ID:
301195298

12.

lean_1mg/L_mouse#4

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #4
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195297
ID:
301195297

13.

lean_1mg/L_mouse#3

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #3
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195296
ID:
301195296

14.

lean_1mg/L_mouse#2

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #2
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195295
ID:
301195295

15.

lean_1mg/L_mouse#1

Organism:
Mus musculus
Source name:
liver tissue from treated lean animal (1mg/L), mouse/replicate #1
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195294
ID:
301195294

16.

ob/ob_0mg/L_mouse#6

Organism:
Mus musculus
Source name:
liver tissue from untreated ob/ob animal, mouse/replicate #6
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195293
ID:
301195293

17.

ob/ob_0mg/L_mouse#5

Organism:
Mus musculus
Source name:
liver tissue from untreated ob/ob animal, mouse/replicate #5
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195292
ID:
301195292

18.

ob/ob_0mg/L_mouse#4

Organism:
Mus musculus
Source name:
liver tissue from untreated ob/ob animal, mouse/replicate #4
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195291
ID:
301195291

19.

ob/ob_0mg/L_mouse#3

Organism:
Mus musculus
Source name:
liver tissue from untreated ob/ob animal, mouse/replicate #3
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195290
ID:
301195290

20.

ob/ob_0mg/L_mouse#2

Organism:
Mus musculus
Source name:
liver tissue from untreated ob/ob animal, mouse/replicate #2
Platform:
GPL7202
Series:
GSE49195
Dataset:
GDS5258
Download data: TXT
Sample
Accession:
GSM1195289
ID:
301195289

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