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1.

Expression data from adult Rattus liver

(Submitter supplied) Activation of the pregnane X receptor (NR1I2) by drugs and other xenobiotics stimulates (or suppresses) expression of numerous genes involved in the metabolic elimination of foreign compounds and some toxic endogenous substrates. We used microarray analysis to identify genes whose expression in rat liver was significantly altered by pregnenolone 16alpha-carbonitrile (PCN) treatment. Keywords: a single ip injection of PCN (100 mg/kg), 8 h treatment
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS2093 GDS2094
Platforms:
GPL341 GPL342
19 Samples
Download data
Series
Accession:
GSE4959
ID:
200004959
2.
Full record GDS2094

Pregnane X receptor agonist effect on the liver (RAE230B)

Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL342
Series:
GSE4959
9 Samples
Download data
3.
Full record GDS2093

Pregnane X receptor agonist effect on the liver (RAE230A)

Analysis of livers of animals treated with pregnenolone 16alpha-carbonitrile (PCN), a pregnane X receptor (NR1I2) agonist. NR1I2 is a member of the nuclear receptor family of ligand-activated transcription factors, and regulates the transcription of genes encoding xenobiotic metabolizing enzymes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL341
Series:
GSE4959
10 Samples
Download data
4.

[RAE230A] Affymetrix Rat Expression 230A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...
Organism:
Rattus norvegicus
68 DataSets
149 Series
2 Related Platforms
3303 Samples
Download data
Platform
Accession:
GPL341
ID:
100000341
5.

[RAE230B] Affymetrix Rat Expression 230B Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html Array B of GeneChip Rat Expression Set 230 Has 15333 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. Sequence clusters were created from Build 99 of UniGene (June 2002) and refined by analysis and comparison with a number of other publicly available databases including the Baylor College of Medicine Human Genome Sequencing Center's preliminary rat genome assembly (June 2002). more...
Organism:
Rattus norvegicus
8 DataSets
16 Series
179 Samples
Download data
Platform
Accession:
GPL342
ID:
100000342
6.

PCN, biological rep5B

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111906
ID:
300111906
7.

PCN, biological rep4b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111904
ID:
300111904
8.

PCN, biological rep3b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111902
ID:
300111902
9.

PCN, biological rep2b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111900
ID:
300111900
10.

PCN, biological rep1b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111898
ID:
300111898
11.

corn oil control, biological rep5b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111896
ID:
300111896
12.

corn oil control, biological rep4b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111894
ID:
300111894
13.

corn oil control, biological rep3b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111892
ID:
300111892
14.

corn oil control, biological rep1b

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL342
Series:
GSE4959
Dataset:
GDS2094
Download data
Sample
Accession:
GSM111889
ID:
300111889
15.

PCN, biological rep5a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111905
ID:
300111905
16.

PCN, biological rep4a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111903
ID:
300111903
17.

PCN, biological rep3a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111901
ID:
300111901
18.

PCN, biological rep2a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111899
ID:
300111899
19.

PCN, biological rep1a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111897
ID:
300111897
20.

corn oil control, biological rep5a

Organism:
Rattus norvegicus
Source name:
Rattus, adult liver
Platform:
GPL341
Series:
GSE4959
Dataset:
GDS2093
Download data
Sample
Accession:
GSM111895
ID:
300111895
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