GSE50501[Accession] - GEO DataSets

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Items: 4

Select item 2000505011.

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair [CL stage]

(Submitter supplied) Cell fate is defined by specific transcriptional program. Here, we provide evidence that the transcriptional coactivator, Mediator 1 (MED1), is critical in determining the cell fate of ectodermal epithelia. MED1 ablation disrupted enamel formation and generated hair adjacent to the incisors. Deletion of MED1 altered the differentiation of dental epithelia to one expressing epidermal and hair genes similar to the skin. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
2 Samples

Download data: TXT

Series

Accession:: GSE50501

ID:: 200050501

Analyze with GEO2R

Select item 1000068852.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...