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Items: 8

1.

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair [mixed stage]

(Submitter supplied) Cell fate is defined by specific transcriptional program. Here, we provide evidence that the transcriptional coactivator, Mediator 1 (MED1), is critical in determining the cell fate of ectodermal epithelia. MED1 ablation disrupted enamel formation and generated hair adjacent to the incisors. Deletion of MED1 altered the differentiation of dental epithelia to one expressing epidermal and hair genes similar to the skin. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
6 Samples
Download data: TXT
Series
Accession:
GSE50503
ID:
200050503
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
881 Series
16514 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

KO 4 wk Mat

Organism:
Mus musculus
Source name:
MED1 KO_4wk_Mat
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220316
ID:
301220316
4.

WT 4 wk Mat

Organism:
Mus musculus
Source name:
Control (WT)_4wk_Mat
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220315
ID:
301220315
5.

KO 4 wk Sec

Organism:
Mus musculus
Source name:
MED1 KO_4wk_Sec
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220314
ID:
301220314
6.

WT 4 wk Sec

Organism:
Mus musculus
Source name:
Control (WT)_4wk_Sec
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220313
ID:
301220313
7.

Knockout (KO) 4 wk CL

Organism:
Mus musculus
Source name:
MED1 KO_4wk_CL
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220312
ID:
301220312
8.

Control (WT) 4 wk CL

Organism:
Mus musculus
Source name:
Control (WT)_4wk_CL
Platform:
GPL6885
Series:
GSE50503 GSE50504
Download data
Sample
Accession:
GSM1220311
ID:
301220311
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Supplemental Content

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