GEO DataSets

(Submitter supplied) This is a study to explore the transcriptional changes after Adjudin treatment in adult rat testes at three time points (control, 8 hour and 4 day). Adjudin, [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide], is a potential male contraceptive that targets the Sertoli-germ cell interface and causes germ cell depletion from the seminiferous epithelium. Adjudin has been proved to be a useful model to study the mechanisms that regulate junction restructuring in the testis. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS2119

Platform:

GPL1355

8 Samples

Download data: CEL, EXP

Analysis of testis from Sprague-Dawleys 8 hours or 4 days after Adjudin treatment. Adjudin targets the Sertoli-germ cell adherens junction and causes germ cell depletion from the seminiferous epithelium. Results provide insight into the mechanisms that regulate junction restructuring in the testis.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 3 time sets

Platform:

GPL1355

Series:

GSE5131

8 Samples

Download data: CEL, EXP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

746 Series

13 Related Platforms

23030 Samples

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