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Items: 15

1.

Progressive loss of PGC-1alpha expression in aging muscle potentiates glucose intolerance and systemic inflammation

(Submitter supplied) Decreased mitochondrial mass and function in muscle of diabetic patients is associated with low PGC-1alpha, a transcriptional coactivator of the mitochondrial gene program. To investigate whether reduced PGC-1alpha and oxidative capacity in muscle directly contributes to age-related glucose intolerance, we compared the genetic signatures and metabolic profiles of aging mice lacking muscle PGC-1alpha. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4904
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE52550
ID:
200052550
2.
Full record GDS4904

Peroxisome proliferator-γ coactivator-1α deficiency effect on aged gastrocnemius muscle

Analysis of muscle from aged animals with muscle-specific Pgc-1α depletion. PGC-1alpha is a transcriptional coactivator of the mitochondrial gene program. Results provide insight into the role of Pgc-1α in the glucose intolerance and chronic systemic inflammation associated with aging.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 age, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE52550
12 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4412 Series
40 Related Platforms
57461 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

BS2011051064

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269630
ID:
301269630
5.

BS2011051063

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269629
ID:
301269629
6.

BS2011051062

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269628
ID:
301269628
7.

BS2011051061

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269627
ID:
301269627
8.

BS2011051060

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269626
ID:
301269626
9.

BS2011051059

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from old (24 month old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269625
ID:
301269625
10.

BS2011051058

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269624
ID:
301269624
11.

BS2011051057

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269623
ID:
301269623
12.

BS2011051056

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) knock-out mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269622
ID:
301269622
13.

BS2011051055

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269621
ID:
301269621
14.

BS2011051054_2

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269620
ID:
301269620
15.

BS2011051053

Organism:
Mus musculus
Source name:
Gastrocnemius muscle mRNA from young (10 week old) wild-type mice
Platform:
GPL1261
Series:
GSE52550
Dataset:
GDS4904
Download data: CEL
Sample
Accession:
GSM1269619
ID:
301269619
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