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Items: 9

1.

Pyruvate induces mitochondrial biogenesis by a PGC-1alpha independent mechanism

(Submitter supplied) The present study examines the impact of altering energy provision on mitochondrial biogenesis in muscle cells. C2C12 myoblasts were chronically treated with supraphysiological levels of sodium pyruvate for 72 hr. Treated cells exhibited increased mitochondrial protein expression, basal respiratory rate and maximal oxidative capacity. The increase in mitochondrial biogenesis was independent of increases in PGC-1alpha and PGC-1alpha mRNA expression. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2265
Platform:
GPL1261
6 Samples
Download data
Series
Accession:
GSE5497
ID:
200005497
2.
Full record GDS2265

Pyruvate effect on muscle cells

Analysis of C2C12 myoblasts treated with supraphysiological levels of sodium pyruvate for 72 hours. Pyruvate increases mitochondrial biogenesis in muscle myoblasts. Results provide insight into the impact of altering energy provision on mitochondrial biogenesis in muscle cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1261
Series:
GSE5497
6 Samples
Download data
DataSet
Accession:
GDS2265
ID:
2265
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4422 Series
40 Related Platforms
57633 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

myoblast_treated_rep3

Organism:
Mus musculus
Source name:
C2C12 myoblasts, treated with 50 mM sodium pyruvate for 72 hr
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126591
ID:
300126591
5.

myoblast_treated_rep2

Organism:
Mus musculus
Source name:
C2C12 myoblasts, treated with 50 mM sodium pyruvate for 72 hr
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126590
ID:
300126590
6.

myoblast_treated_rep1

Organism:
Mus musculus
Source name:
C2C12 myoblasts, treated with 50 mM sodium pyruvate for 72 hr
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126589
ID:
300126589
7.

myoblast_untreated_rep3

Organism:
Mus musculus
Source name:
C2C12 myoblasts, untreated, replicate 3
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126588
ID:
300126588
8.

myoblast_untreated_rep2

Organism:
Mus musculus
Source name:
C2C12 myoblasts, untreated
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126587
ID:
300126587
9.

myoblast_untreated_rep1

Organism:
Mus musculus
Source name:
C2C12 myoblasts, untreated
Platform:
GPL1261
Series:
GSE5497
Dataset:
GDS2265
Download data
Sample
Accession:
GSM126586
ID:
300126586
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Supplemental Content

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