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Items: 4

1.

Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates (small RNA AGO-IP)

(Submitter supplied) Dicer is a deeply conserved endoribonuclease with key functions in small RNA biogenesis. Here we employed PAR-CLIP/iPAR-CLIP to identify direct Dicer binding sites in the transcriptomes of human cells and human. We found hundreds of novel miRNAs and non-canonical Dicer substrates with high sensitivity. Small RNA production depended on structure of the binding site and is globally biased towards the 5' arm of hairpins. more...
Organism:
Homo sapiens
Type:
Other; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
2 Samples
Download data: GFF, TSV, WIG
Series
Accession:
GSE55331
ID:
200055331
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

FLAG:AGO3 loaded small RNA

Organism:
Homo sapiens
Source name:
cell culture
Platform:
GPL11154
Series:
GSE55331 GSE55333
Download data: TSV
Sample
Accession:
GSM1334331
ID:
301334331
4.

FLAG:AGO2 loaded small RNA

Organism:
Homo sapiens
Source name:
cell culture
Platform:
GPL11154
Series:
GSE55331 GSE55333
Download data: TSV
Sample
Accession:
GSM1334330
ID:
301334330
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Supplemental Content

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