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Items: 11

1.

Lin28 sustains early renal progenitors and induces Wilms tumor

(Submitter supplied) Wilms Tumor, the most common pediatric kidney cancer, evolves from the failure of terminal differentiation of the embryonic kidney. Here we show that over-expression of the heterochronic regulator Lin28 during kidney development in mice markedly expands nephrogenic progenitors by blocking their final wave of differentiation, ultimately resulting in pathology highly reminiscent of Wilms tumor.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5415
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE56323
ID:
200056323
2.
Full record GDS5415

Model for Wilms tumor of the kidney: time course

Analysis of kidney tumors from Lin28a transgenics at 5 weeks and 4 months of age. Overexpression of heterochronic regulator Lin28 during kidney development promotes Wilms tumor formation. Results provide insight into the role of Lin28 in Wilms tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 2 disease state sets
Platform:
GPL6885
Series:
GSE56323
8 Samples
Download data
3.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
878 Series
16455 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
4.

control kidney #4

Organism:
Mus musculus
Source name:
control kidney #4
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359102
ID:
301359102
5.

kidney tumor #4

Organism:
Mus musculus
Source name:
kidney tumor #4
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359101
ID:
301359101
6.

control kidney #3

Organism:
Mus musculus
Source name:
control kidney #3
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359100
ID:
301359100
7.

kidney tumor #3

Organism:
Mus musculus
Source name:
kidney tumor #3
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359099
ID:
301359099
8.

control kidney #2

Organism:
Mus musculus
Source name:
control kidney #2
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359098
ID:
301359098
9.

kidney tumor #2

Organism:
Mus musculus
Source name:
kidney tumor #2
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359097
ID:
301359097
10.

control kidney #1

Organism:
Mus musculus
Source name:
control kidney #1
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359096
ID:
301359096
11.

kidney tumor #1

Organism:
Mus musculus
Source name:
kidney tumor #1
Platform:
GPL6885
Series:
GSE56323
Dataset:
GDS5415
Download data
Sample
Accession:
GSM1359095
ID:
301359095
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Supplemental Content

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