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Items: 10

1.

Cancerous inhibitor of Protein Phosphatase 2A is a novel cell-autonomous regulator governing both T-and B-cell activation in vivo

(Submitter supplied) The generation of optimal immune response requires combined activation of both T- and B-cells. Here, we demonstrate that the cancerous inhibitor of protein phosphatase 2A (CIP2A) is a novel factor that governs activation of both T- and B-cells in vivo. Upon ovalbumin challenge, CIP2A-deficient (CIP2AHOZ) mice show impaired immune response. Furthermore, CIP2AHOZ mice had impaired clearance of Listeria Monocytogenesis (L.m.) infection, combined with decreased numbers of CD8+ T-cells and IFN-γ secretion. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE56401
ID:
200056401
2.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
33 DataSets
881 Series
16514 Samples
Download data: BGX
Platform
Accession:
GPL6885
ID:
100006885
3.

spleen_Cip2a_rep4

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360897
ID:
301360897
4.

spleen_Cip2a_rep3

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360896
ID:
301360896
5.

spleen_Cip2a_rep2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360895
ID:
301360895
6.

spleen_Cip2a_rep1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360894
ID:
301360894
7.

spleen_wt_rep4

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360893
ID:
301360893
8.

spleen_wt_rep3

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360892
ID:
301360892
9.

spleen_wt_rep2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360891
ID:
301360891
10.

spleen_wt_rep1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL6885
Series:
GSE56401
Download data
Sample
Accession:
GSM1360890
ID:
301360890
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Supplemental Content

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