GEO DataSets

(Submitter supplied) Gene expression of mouse hepatoblasts (HBs) expressing IDH1 WT, IDH1 R132C, IDH2 WT, R172K and empty vector controls (N=2 cultures for each condition) grown on collagen-coated plates and IDH1 R132C and empty vector controls on uncoated plates were evaluated using Affymetrix Mouse 430Av2 DNA microarrays that were processed at the Dana-Farber Cancer Institute core facility (http://macf-web.dfci.harvard.edu/) using their standard protocol. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS5676 GDS5677

Platform:

GPL8321

14 Samples

Download data: CEL

Analysis of mutant IDH1 (R132C)-expressing hepatoblasts that were grown on uncoated plates to induce hepatocyte differentiation. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into the role of IDH1 in hepatocyte differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL8321

Series:

GSE57002

4 Samples

Download data: CEL

Analysis of hepatoblasts expressing mutant IDH1 (R132C) and mutant IDH2 (R172K) grown on collagen-coated plates. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into molecular pathways by which IDH mutations lead to tumor formation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 5 genotype/variation sets

Platform:

GPL8321

Series:

GSE57002

10 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...

Organism:

Mus musculus

66 DataSets

522 Series

2 Related Platforms

6848 Samples

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