GEO DataSets

(Submitter supplied) Oligodendrocytes undergo extensive changes as they differentiate from progenitors into myelinating cells. To better understand the molecular mechanisms underlying this transformation, we performed a comparative analysis using gene expression profiling of A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes. Cells were sort-purified ex vivo from postnatal rat brain using flow cytometry. Using Affymetrix microarrays, 1707 transcripts were identified with a more than twofold increase in expression inO4+oligodendrocytes. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS2379 GDS2380

Platforms:

GPL341 GPL342

18 Samples

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Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage sets

Platform:

GPL342

Series:

GSE5940

9 Samples

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Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage sets

Platform:

GPL341

Series:

GSE5940

9 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...

Organism:

Rattus norvegicus

68 DataSets

148 Series

2 Related Platforms

3292 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html Array B of GeneChip Rat Expression Set 230 Has 15333 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. Sequence clusters were created from Build 99 of UniGene (June 2002) and refined by analysis and comparison with a number of other publicly available databases including the Baylor College of Medicine Human Genome Sequencing Center's preliminary rat genome assembly (June 2002). more...

Organism:

Rattus norvegicus

8 DataSets

16 Series

179 Samples

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