GSE6376[Accession] - GEO DataSets

Select item 2000063761.

Zymosan stimulation of MyD88-deficient bone marrow-derived macrophages

(Submitter supplied) Innate immune pattern recognition receptors play critical roles in pathogen detection and initiation of antimicrobial responses. We and others have previously demonstrated the importance of the beta-glucan receptor Dectin-1 in the recognition of pathogenic fungi by macrophages and dendritic cells, and have elucidated some of the mechanisms by which Dectin-1 signals to coordinate the antifungal response. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2686
Platform:: GPL1261
4 Samples

Download data: CEL, EXP

Series

Accession:: GSE6376

ID:: 200006376

Select item 26862.

MyD88 deficient macrophage response to zymosan

Analysis of MyD88-deficient macrophages treated with fungal cell wall component zymosan. Zymosan-induced Toll-like receptor (TLR) signaling is transduced via adaptor protein MyD88. Results provide insight into the role of non-TLR innate immune signaling in response to zymosan and pathogenic fungi.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL1261
Series:: GSE6376
4 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2686

ID:: 2686

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...