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Items: 9

1.

Expression data from KSL and GMP cells of FLT3/ITD and FLT3/ITD-SmoM2 mice

(Submitter supplied) FLT3/ITD-SmoM2 mice developed rapidly fatal myeloid leukemia compared to FLT3/ITD only mice, suggesting that overactivation of the Hedgehog signaling pathway via SmoM2 can drive myeloid disease progression We used the Affymetrix Mouse 430_2.0 microarray to detail global gene expression responsible for disease progression in sorted bone marrow cells and found that the Hedgehog signaling pathway contributes to disease progression by enhancing FLT3 signaling
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5806
Platform:
GPL1261
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE67134
ID:
200067134
2.
Full record GDS5806

FLT3/ITD-SmoM2 acute myeloid leukemia model: sorted bone marrow cells

Analysis of KSL and GMP cells isolated from bone marrow of Flt3/ITD-SmoM2 transgenics at around 3 months of age when they developed leukemia. Wild-type and FLT3/ITD littermates of the FLT3/ITD-SmoM2 animals were also examined. Results provide insight into the role of SmoM2 in leukemic progression.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE67134
6 Samples
Download data: CEL, CHP
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4456 Series
40 Related Platforms
57985 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

KSL cells from FLT3/ITD-SmoM2 mouse bone marrow

Organism:
Mus musculus
Source name:
FLT3/ITD-SmoM2 KSL
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639872
ID:
301639872
5.

GMP cells from FLT3/ITD-SmoM2 mouse bone marrow

Organism:
Mus musculus
Source name:
FLT3/ITD-SmoM2 GMP
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639871
ID:
301639871
6.

KSL cells from FLT3/ITD bone marrow

Organism:
Mus musculus
Source name:
FLT3/ITD KSL
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639870
ID:
301639870
7.

GMP cells from FLT3/ITD mouse bone marrow

Organism:
Mus musculus
Source name:
FLT3/ITD GMP
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639869
ID:
301639869
8.

KSL cells from wild type bone marrow

Organism:
Mus musculus
Source name:
WT KSL
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639868
ID:
301639868
9.

GMP cells from wild type mouse bone marrow

Organism:
Mus musculus
Source name:
WT GMP
Platform:
GPL1261
Series:
GSE67134
Dataset:
GDS5806
Download data: CEL, CHP
Sample
Accession:
GSM1639867
ID:
301639867
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Supplemental Content

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