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Items: 6

1.

CD4+ T cells gene-transduced with AML1, wild type Foxp3, and a Foxp3 mutant defective in binding to AML1

(Submitter supplied) To clarify how Foxp3 regulates its target genes, we performed co-immunoprecipitation experiments and found that Foxp3 physically bound to AML1/Runx1 (Ono, M. et al, Nature, 2007). In this series of study, we compared gene regulations by AML1, wild type Foxp3, and a Foxp3 mutant with defective binding to AML1. Keywords: Retroviral gene-transduction into primary CD4+ T cells
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE6939
ID:
200006939
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4427 Series
40 Related Platforms
57689 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
3.

Foxp3 mutant

Organism:
Mus musculus
Source name:
CD4+ T cells gene-transduced with a Foxp3 mutant defective in binding to AML1.
Platform:
GPL1261
Series:
GSE6939
Download data: CEL
Sample
Accession:
GSM160042
ID:
300160042
4.

wild type Foxp3

Organism:
Mus musculus
Source name:
CD4+ T cells gene-transduced with wild type Foxp3
Platform:
GPL1261
Series:
GSE6939
Download data: CEL
Sample
Accession:
GSM160041
ID:
300160041
5.

AML1

Organism:
Mus musculus
Source name:
CD4+ T cells gene-transduced with AML1
Platform:
GPL1261
Series:
GSE6939
Download data: CEL
Sample
Accession:
GSM160039
ID:
300160039
6.

empty vector

Organism:
Mus musculus
Source name:
CD4+ T cells gene-transduced with empty vector
Platform:
GPL1261
Series:
GSE6939
Download data: CEL
Sample
Accession:
GSM160037
ID:
300160037
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