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Items: 12

1.

Comparative analysis of gene expression WT and Nrf2-/- mice Type II cells

(Submitter supplied) We hypothesize that gene expression in the Type II cells of Nrf2+/+ and Nrf2-/- mice are divergent thus contributing the cell growth. More specifically, type II cells from Nrf2-/- mice have increased reactive oxygen species that cause the impaired cell growth. In order to test these hypotheses at the gene expression level, we utilized microarray analysis to examine transcriptional differences between Nrf2+/+ and Nrf2-/- cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2875
Platform:
GPL1261
9 Samples
Download data: CEL
Series
Accession:
GSE7810
ID:
200007810
2.
Full record GDS2875

Nrf2-deficient type II lung epithelial cell response to antioxidant supplementation

Analysis of Nrf2 deficient lung epithelial cells treated with the antioxidant glutathione (GSH). GSH rescues cells from prooxidant-induced lung injury associated with Nrf2 deficiency. Results provide insight into the molecular mechanisms by which Nrf2 regulates cellular protection and proliferation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE7810
6 Samples
Download data: CEL
DataSet
Accession:
GDS2875
ID:
2875
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4427 Series
40 Related Platforms
57689 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

MNR 3-3 KO Treated 4

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse supplemented with GSH.
Platform:
GPL1261
Series:
GSE7810
Download data: CEL
Sample
Accession:
GSM227713
ID:
300227713
5.

MNR 2-3 KO 4

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse.
Platform:
GPL1261
Series:
GSE7810
Download data: CEL
Sample
Accession:
GSM227712
ID:
300227712
6.

MNR 1-3 WT 5

Organism:
Mus musculus
Source name:
Type II cells from Nrf2+/+ mouse.
Platform:
GPL1261
Series:
GSE7810
Download data: CEL
Sample
Accession:
GSM227711
ID:
300227711
7.

MNR 8-2 KO Treated 3

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse supplemented with GSH.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189479
ID:
300189479
8.

MNR 7-2 KO Treated 2

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse supplemented with GSH.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189478
ID:
300189478
9.

MNR 6-2 KO 3

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189477
ID:
300189477
10.

MNR 5-2 KO 2

Organism:
Mus musculus
Source name:
Type II cells from Nrf2-/- mouse.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189476
ID:
300189476
11.

MNR 2-2 WT 4

Organism:
Mus musculus
Source name:
Type II cells from Nrf2+/+ mouse.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189473
ID:
300189473
12.

MNR 1-2 WT 3

Organism:
Mus musculus
Source name:
Type II cells from Nrf2+/+ mouse.
Platform:
GPL1261
Series:
GSE7810
Dataset:
GDS2875
Download data: CEL
Sample
Accession:
GSM189472
ID:
300189472
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