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Items: 5

1.

Dnmt3l-/+ (maternal methylation-deficient) vs normal 8.5dpc embryos

(Submitter supplied) During oogenesis, DNA methyltransferase 3-like (Dnmt3l) is required for the establishment of the maternal germline DNA methylation imprints that in the offspring, govern the parent-of-origin-specific expression of most known imprinted genes (Science 2001, 294:2536-9). Dnmt3l-deficient dams were crossed with wildtype sires to obtain Dnmt3l-/+ embryos that lack maternal methylation imprints. Gene expression was measured in Dnmt3l-/+ and wildtype embryos and is expected to differ for imprinted genes that are under the control of a maternal methylation mark. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
3 Samples
Download data: CEL, CHP
Series
Accession:
GSE8756
ID:
200008756
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4538 Series
40 Related Platforms
58877 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
3.

embryo_Dnmt3l-/+_8.5dpc_rep2

Organism:
Mus musculus
Source name:
whole embryo, Dnmt3l-/+ 8.5dpc maternal methylation-deficient mutant
Platform:
GPL1261
Series:
GSE8756
Download data: CEL, CHP
Sample
Accession:
GSM217369
ID:
300217369
4.

embryo_Dnmt3l-/+_8.5dpc_rep1

Organism:
Mus musculus
Source name:
whole embryo, Dnmt3l-/+ 8.5dpc maternal methylation-deficient mutant
Platform:
GPL1261
Series:
GSE8756
Download data: CEL, CHP
Sample
Accession:
GSM217368
ID:
300217368
5.

embryo_normal_8.5dpc_control

Organism:
Mus musculus
Source name:
whole embryo, normal (non-methylation mutant) 8.5dpc control
Platform:
GPL1261
Series:
GSE8756
Download data: CEL, CHP
Sample
Accession:
GSM217367
ID:
300217367
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