GSE8868[Accession] - GEO DataSets

Select item 2000088681.

Comparison of splenic and small intestine lamina propria macrophages

(Submitter supplied) The intestinal immune system must elicit robust immunity against harmful pathogens but restrain immune responses directed against commensal microbes and dietary antigens. The mechanisms that maintain this dichotomy are poorly understood. Here we describe a population of CD11b+F4/80+CD11c– macrophages in the lamina propria (LP) that express several anti-inflammatory molecules including interleukin 10 (IL-10), but little or no pro-inflammatory cytokines, even upon stimulation with Toll-like receptor (TLR) ligands. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2982
Platform:: GPL1261
4 Samples

Download data: CEL, CHP

Series

Accession:: GSE8868

ID:: 200008868

Select item 29822.

CD11b-plus CD11c-minus macrophages of the intestinal lamina propria

Comparison of CD11b+ CD11c- macrophages of the small intestinal lamina propria and the spleen. The intestinal immune system responds robustly to pathogens yet remains tolerant to commensals and food antigens. Results provide insight into the role of intestinal macrophages in immune tolerance.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 cell type sets

Platform:: GPL1261
Series:: GSE8868
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2982

ID:: 2982

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...