GEO DataSets

(Submitter supplied) The liver is frequently challenged by surgery-induced metabolic overload, viruses, or toxins, which induce the formation of reactive oxygen species. To determine the effect of oxidative stress on liver regeneration and to identify the underlying signalling pathways, we studied liver repair in mice lacking the Nrf2 transcription factor. In these animals, expression of several cytoprotective enzymes was reduced in hepatocytes, resulting in oxidative stress. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3406

Platform:

GPL1261

6 Samples

Download data: CEL, CHP

Analysis of livers from animals lacking Nrf2, a transcription factor involved in the defense against oxidative stress. The liver is often exposed to oxidative stresses, such as those induced by viruses, toxins, and surgery. Results provide insight into the role of Nrf2 in liver regeneration.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1261

Series:

GSE8969

6 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4538 Series

40 Related Platforms

58877 Samples

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