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Items: 4

1.

A novel approach to investigate tissue-specific trinucleotide repeat instability - A validation set of prediction model

(Submitter supplied) In Huntington’s disease (HD), an expanded CAG repeat produces characteristic striatal neurodegeneration. Interestingly, the HD CAG repeat, whose length determines age at onset, undergoes tissue-specific somatic instability, predominant in the striatum, suggesting that tissue-specific CAG length changes could modify the disease process. Therefore, understanding the mechanisms underlying the tissue specificity of somatic instability may provide novel routes to therapies. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
2 Samples
Download data: CEL
Series
Accession:
GSE9025
ID:
200009025
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4423 Series
40 Related Platforms
57646 Samples
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Platform
Accession:
GPL1261
ID:
100001261
3.

HdhQ111/Hdh+ cerebellum at 5 months

Organism:
Mus musculus
Source name:
HdhQ111/Hdh+ cerebellum at 5 months
Platform:
GPL1261
Series:
GSE9025
Download data: CEL
Sample
Accession:
GSM228968
ID:
300228968
4.

HdhQ111/Hdh+ striatum at 5 months

Organism:
Mus musculus
Source name:
HdhQ111/Hdh+ striatum at 5 months
Platform:
GPL1261
Series:
GSE9025
Download data: CEL
Sample
Accession:
GSM228967
ID:
300228967
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