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Items: 10

1.

In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity

(Submitter supplied) The identification of small molecules which either increase the number and/or enhance the activity of CD34+ hematopoietic stem and progenitor cells (HSPCs) during ex-vivo expansion has remained challenging. Applying an unbiased in vivo chemical screen in a transgenic (c-myb:EGFP) zebrafish embryo model, histone deacetylase inhibitors (HDACI) (valproic acid, resminostat and entinostat) were shown to significantly amplify the number of phenotypic hematopoietic precursors. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
8 Samples
Download data: CSV
Series
Accession:
GSE90552
ID:
200090552

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11754 Series
331536 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

Valproic_Acid_4

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406741
ID:
302406741

SRA Run Selector

4.

Valproic_Acid_3

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406740
ID:
302406740

SRA Run Selector

5.

Valproic_Acid_2

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406739
ID:
302406739

SRA Run Selector

6.

Valproic_Acid_1

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406738
ID:
302406738

SRA Run Selector

7.

PBS_4

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406737
ID:
302406737

SRA Run Selector

8.

PBS_3

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406736
ID:
302406736

SRA Run Selector

9.

PBS_2

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406735
ID:
302406735

SRA Run Selector

10.

PBS_1

Organism:
Homo sapiens
Source name:
G-CSF mobilized peripheral blood stem cells
Platform:
GPL16791
Series:
GSE90552
Download data
Sample
Accession:
GSM2406734
ID:
302406734

SRA Run Selector

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db=gds|term=GSE90552[Accession]|query=1|qty=2|blobid=MCID_662a8a1a862bea0a3fd5a932|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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